2010 AnnuAl REpoRT - Ciberdem

Diabetes and obesity:
biopathology and cellular plasticity
Institut d’Investigacions Biomèdiques August Pi i Sunyer, Barcelona
www.diabetisiobesitat.org
Principal Investigator Ramon Gomis rgomis@clinic.ub.es Associate researchers Roser Casamitjana, Ignacio Conget, Enric Esmatjes,
Liliam Flores, Rosa Gasa, Felicia Hanzu, Marga Giménez, Belén Nadal, Marcelina Parrizas, Josep Vidal, Emilio Ortega, Sara Cervantes,
M Carmen Carmona, Marc Claret, María José Coves Postdoctoral fellows Rebeca Fernández, Nathalie Nicod, Sandra Rebuffat
PhD students Jordi Altirriba, Marta Amigó, Joana Duarte, Miriam Ejarque, Katerina Papageorgiou, Fabián Pardo, Gemma Pujadas
Lab manager Marta Julià Lab technicians Yaiza Esteban, Ainhoa García, Sandra Piquer, Lídia Sánchez
Total IF: 31.889
Publications: 7, 2 of them in the first decile, 3 in the first quartile
and 2 in the second quartile
With other CIBERDEM groups: 2
Research grants: 10
European projects: 2
National projects: 5
Autonomous Community projects: 2
Private funds: 1
Scientific collaborations within CIBERDEM: 7
Clinical trials: 8
PhD theses: 3
Keywords
Clinical diabetes. Endothelium. Islet degeneration and
damage. Islet development. Weight regulation and obesity.
Main lines of research
-The effects of pancreatic-mesenteric adipose tissue on
beta cell plasticity.
-Crosstalk between adipose tissue and endothelium in
obesity and type 2 diabetes: the role of adipocytokines
in the aetiology and development of the atherothrombotic
complications in both diseases.
-The molecular determinants involved in pancreatic
beta-cell apoptosis and regeneration: clinical
applications.
-Transcriptional networks which control beta-cell population
and function.
-Metabolic and molecular targets of the antidiabetic effect
of sodium tungstate.
-The role of the hypothalamus in energy homeostasis control in
obesity.
2010 Annual Report
111