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SOFT 2004 Meeting Abstracts - Society of Forensic Toxicologists

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AS <br />

SURVEY ON FORENSIC TOXICOLOGICAL ANALYTICAL LABORATORIES IN BRAZIL<br />

E.F. Mendes, V.F. Barbosa, N.F.G. Pereira, and A.M. Chasin*, REBLAS/ANVISA I Brazil; <strong>Forensic</strong><br />

Toxicology Lab, Medical Legal Institute- SP and College <strong>of</strong>Phannacy Oswaldo Cruz, Sao Paulo- Brazil<br />

<strong>Forensic</strong> Toxicology in Brazil is carried out, principally, by public laboratories, except for Doping and<br />

Workplace Drug Testing that are done in private laboratories. Compared to other countries, there are neither<br />

established guidelines to orient these analyses nor a system <strong>of</strong> certification to orient Toxicological Analyses,<br />

in general, and specifically for forensic purposes.<br />

This paper had as objectives the following: to identify the laboratories that work with or have the potential to<br />

carry out tests pertaining to <strong>Forensic</strong> Toxicology and the respective assays, as required by the current public<br />

health legislation, as well as the methodologies used and the Quality Systems followed by this labs; to<br />

evaluate, beforehand, the technical capacity <strong>of</strong> these laboratories and what they must do in order to be<br />

qualified by the Brazilian Network <strong>of</strong> Laboratories in Public Health REBLAS/ANVISA (the Brazilian<br />

Agency for Health and Sanitary Safety Vigilance and Management).<br />

A survey was prepared <strong>of</strong> several assays carried out by the labs and were divided in three major groups:<br />

Group I - Analysis <strong>of</strong> Controlled Substances and Abusive Drugs in materials seized by the Police (in natura),<br />

with 120 assays; Group II - Presumptive Tests and Confinnation <strong>of</strong> Controlled Substances and Abusive<br />

Drugs in Biological Matrices in vivo, with 1000 assays; Group III Presumptive Tests and Confirmation <strong>of</strong><br />

Controlled Substances and Abusive Drugs in Biological Matrices post mortem, with 906 assays. Also<br />

included were a "Survey on Quality Systems" and a "Registration Card".<br />

The surveys were prepared with the aim <strong>of</strong> dividing substances up into categories and respective subcategories,<br />

with the most representative substance tests being included. The presumptive and the confinnation<br />

tests were included for all groups. Fifteen labpratories, representing all Brazilian geographic regions, took part<br />

in the research. The regions <strong>of</strong> South and Southeast Brazil were the most represented, each one with six<br />

participating laboratories, although the regions <strong>of</strong> North, Northeast and Middle-East Brazil also participated,<br />

with only one laboratory, however, presenting analyses <strong>of</strong> Group I. Of the 15 laboratories taking part in the<br />

research, only 9 <strong>of</strong> them answered to the Group I survey; 3 answered to both Group I and Group II; 2<br />

laboratories answered only to Group II and only 1 laboratory, located in Southeast Brazil, declared that they<br />

had completely carried out the Group III survey.<br />

Most <strong>of</strong> the laboratories taking part (80%) carried out the Group I assays- Analysis <strong>of</strong> Control led Substances<br />

and Abusive Drugs. Group II Presumptive Tests and Confirmation <strong>of</strong> Controlled Substances and Abusive<br />

. Drugs in Biological Matrices in vivo was carried out by 33% <strong>of</strong> the institutions and Group III - Presumptive<br />

Test and Confirmation <strong>of</strong> Controlled Substances and Abusive Drugs in Biological Matrices post mortem was<br />

carried out by only one laboratory (6.6% <strong>of</strong> the laboratories studied). It was concluded that 26% <strong>of</strong> the<br />

laboratories taking part in the research still do not follow any <strong>of</strong> the quality parameters. The infonnation from<br />

the Survey will serve as a basis for preparing policies, establishing and managing <strong>Forensic</strong> Toxicological<br />

Laboratories in Brazil.<br />

Keywords: Brazil, <strong>Forensic</strong> Laboratories, Survey<br />

Page 119

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