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SOFT 2004 Meeting Abstracts - Society of Forensic Toxicologists

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P38 <br />

TREND OF ACUTE NARCOTISM DURING THE LAST TEN YEARS<br />

Nadia Fucci"', Nadia De Giovanni, Fabio De Giorgio, Marcello Chiarotti<br />

Istituto di Medicina Legale e delle Assicurazioni, Universita Cattolica del Sacro Cuore, L.go F. Vito,1 ­<br />

00168 Roma (Italy)<br />

Since 1993 the Laboratory <strong>of</strong> <strong>Forensic</strong> Toxicology at the Catholic University <strong>of</strong> Rome has evaluated the<br />

trends <strong>of</strong> deaths from narcotism ..We have already studied previous periods and our data were compared<br />

with D.C.S.A. (Dipartimento Centrale Servizi Antidroga - Central Antidrug Department) and GTF (Gruppo<br />

Tossicologi Forensi - Italian <strong>Forensic</strong> Toxicologist Association) informations. In this paper we present a<br />

statistical analysis <strong>of</strong> the lethal intoxications in the period 2000-2003 and compare to two prior periods<br />

(period A 1993-1996; period B 1997-1999).<br />

Annually cruel deaths observed by the Legal Medicine Institute <strong>of</strong> Catholic University range between 300<br />

to 400. About 18-22% <strong>of</strong> these cases are submitted for toxicologic analyses; less than 10% <strong>of</strong> total deaths<br />

could be referred to lethal intoxications.<br />

Analysis <strong>of</strong> data showed interesting observations relative to the last ten years:<br />

• A decreasing in overdose cases<br />

• Morphine alone is stiil the main drug accounting for death<br />

• An increase in methadone-related-deaths<br />

• A slight reduction in cases <strong>of</strong> acute cocaine intoxications<br />

A separate study on morphine and ethanol related deaths was performed; this study showed that the<br />

presence <strong>of</strong> ethanol higher than 0.5 gil was more significant when morphine concentrations ranged<br />

between 20 and 250 ng/m!.<br />

Our study suggests the usefulness <strong>of</strong> periodic review <strong>of</strong> mortality phenomena related to drug intoxications.<br />

Keywords: acute narcotism, statistical evaluation, postmortem<br />

Page 373

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