SOFT 2004 Meeting Abstracts - Society of Forensic Toxicologists

P34
DETERMINA TION OF PERMETHRIN, ETHYLBENZENE, XYLENE AND THEIR METABOLITES IN
AN ACUTE INGESTION OF INSECTICIDE
Justin L. Poklis* I, Jeri D. Ropero-Miller l , Diana Garside l , William KeIly2 and Ruth E. Winecker l . IOffice
of the Chief Medical Examiner, 100l Brinkhous-Bullitt Building, Chapel Hill, NC 27599 U.S.A. 2Coastal
Pathology Associates, PO Box 317 Western Boulevard, Jacksonville, NC 28546 U.S.A.
The case history and toxicological findings of an acute ingestion of the insecticide permethrin in a 7 year
old female found in bed with vomit and blood on her face are presented. Permethrin and its carriers,
ethylbenzene and xylene, are all components found in the commercial product, Atroban. The concentration
of permethrin was measured in the liver, aortic blood and gastric content using gas chromatography-mass
spectrometry (GCIMS). Concentrations of ethylbenzene and xylene were measured in the same biological
samples by headspace-gas chromatography. Blood and liver concentrations of permethrin, ethyl benzene
and xylene were detected at concentrations below the lowest curve calibrator. Therefore, permethrin and
ethylbenzene were reported as < 1.0 mgIL(kg), and xylene as