SOFT 2004 Meeting Abstracts - Society of Forensic Toxicologists

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F4
IODINE CONTAINING ADULTERANT -
DETECTION BY INTECT® 8
ITS EFFECT ON RAPID DRUG SCREEN AND
Beckie Chien*, Jan Sook, Raphael C. Wong, Branan Medical Corporation, Irvine, CA, USA
Aims:New generation of commercial adulterants have included iodine as the main ingredient at sample
concentration of about 1 mg per ml. The objective of this study was to evaluate iodine's effect on a certain
rapid drug screen and its detection by an onsite adulterant dipstick, Intect®8.
Method: The adulteration effect of iodine was studied by adding iodine to a urine sample containing three
times the SAMHSA cut-off concentrations of five drugs including benzoyl ecgonine (COC), morphine
(OPI), amphetamine (AMP), THC and PCP. The final concentration of iodine in the sample was 1 mg/mt.
The adulterated sample was then tested by an onsite rapid drug screen Monitect® PCll over one hour
period. The same sample was also tested with the new Intect 8 onsite adulteration test strip that contains g
test pads including creatinine (CR), nitrite (NI), glutaraldehye CGL), pH, specific gravity (SG), bleach (BL),
pyridinium chlorochromate (PCC) and iodine (I) to evaluate the adulterant's detection over time.
Results: Negative (-) result in the drug screen indicates adulterant was able to modify the positive drug test
result to negative result whereas (+1-) indicates a possible adulteration effect for that specific drug; normal
(N) result in the Intect 8 pad suggests no effect of iodine on the specific test pad while abnormal (A)
indicates detection ofthe adulterant by the specific pad.
! Time (min.) COC OPI I AMP I THC PCP
Drug 5 Invalid results due to no control line
i
Screen 10 +
+ + I -
+
Result 30 + + L + I - +
60 + +1­ I + I - +
Time I· CR I Nl GL I ~H SG BL PCC L I
I
5 I N I N N N N A A I A
Intect 8
Result
10 N : N N N N A A I
I
A
30 N j N N N N A A I A
60 I N 1 N N N N N N I N
I
Urine spiked with PCC or BL did not cause an abnormal result with the Iodine pad.
Conclusion: Iodine containing adulterant is shown to mask the presence ofTHC. It also has some effect on
opiate. This adulterant is detectable by an onsite adulteration test device Intect®g in a 30-minute window.
Keywords: Adulteration, Intect, iodine
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