DISPATCHES9. Abravanel F, Sandres-Saune K, Lhomme S, Dubois M,Mansuy JM, Izopet J. Genotype 3 diversity and quantification ofhepatitis E virus RNA. J Clin Microbiol. 2012;50:897–902.http://dx.doi.org/10.1128/JCM.05942-1110. Rose N, Lunazzi A, Dorenlor V, Merbah T, Eono F, Eloit M,et al. High prevalence of hepatitis E virus in French domestic pigs.Comp Immunol Microbiol Infect Dis. 2011;34:419–27.http://dx.doi.org/10.1016/j.cimid.2011.07.00311. Bouquet J, Tesse S, Lunazzi A, Eloit M, Rose N, Nicand E, et al.Close similarity between sequences of hepatitis E virus recoveredfrom humans and swine, France, 2008–2009. Emerg Infect Dis.2011;17:2018–25. http://dx.doi.org/10.3201/eid1711.11061612. Colson P, Borentain P, Queyriaux B, Kaba M, Moal V, Gallian P,et al. Pig liver sausage as a source of hepatitis E virus transmissionto humans. J Infect Dis. 2010;202:825–34. http://dx.doi.org/10.1086/65589813. Pavio N, Merbah T, Thebault A. Frequent hepatitis E viruscontamination in food containing raw pork liver, France.Emerg Infect Dis. 2014;20:1925–7. http://dx.doi.org/10.3201/eid2011.14089114. Lack JB, Volk K, Van Den Bussche RA. Hepatitis E virus genotype3 in wild rats, United States. Emerg Infect Dis. 2012;18:1268–73.http://dx.doi.org/10.3201/eid1808.120070.15. Barnaud E, Rogee S, Garry P, Rose N, Pavio N. Thermalinactivation of infectious hepatitis E virus in experimentallycontaminated food. Appl Environ Microbiol. 2012;78:5153–9.http://dx.doi.org/10.1128/AEM.00436-12Address for correspondence: Jacques Izopet, Institut Fédératif deBiologie de Purpan, Laboratoire de Virologie, 330 Ave de GrandeBretagne, Toulouse 31059, France; email: izopet.j@chu-toulouse.frFebruary 2015:Complicated DatasetsIncluding:• Entry Screening for InfectiousDiseases in Humans• Timing of Influeznza A(H5N1) inPoultry and Humans andSeasonal Influenza ActivityWorldwide, 2004–2013• Quantifying ReportingTimeliness to Improve OutbreakControl• Tickborne Relapsing Fever,Bitterroot Valley, Montana, USA• Simulation Study of the Effect ofInfluenza and InfluenzaVaccination on Risk of AcquiringGuillain-Barré Syndrome• Evidence for Elizabethkingiaanophelis Transmission fromMother to Infant, Hong Kong• Microbiota that Affect Risk forShigellosis in Children inLow-Income Countries• pH Level as a Marker forPredicting Death among Patientswith Vibrio vulnificus Infection,South Korea, 2000–2011http://wwwnc.cdc.gov/eid/content/21/2/contents.htm1226 Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 21, No. 7, July 2015
Asymptomatic Malaria and Other Infectionsin Children Adopted from Ethiopia,United States, 2006–2011Senait M. Adebo, Judith K. Eckerle,Mary E. Andrews, Cynthia R. Howard,Chandy C. JohnWe screened 52 children adopted from Ethiopia for malariabecause they had previously lived in a disease-endemic regionor had past or current hepatomegaly or splenomegaly.Seven (13.5%) children had asymptomatic malaria parasitemiaby microscopy (n = 2) or PCR (n = 5). Our findingssuggest that adoptees at risk for asymptomatic malariashould be screened, preferably by PCR.International adoptees are at increased risk for infectiousdiseases (1). During 2007–2012, Ethiopia was 1 of thetop 5 countries of origin for children who were adoptedby persons in the United States (2), but few studies havebeen published on children from Ethiopia who were adoptedby persons in the United States (3). Malaria causedby Plasmodium falciparum, P. vivax, and, less frequently,P. ovale is endemic to several regions in Ethiopia (4). Childrenadopted from Ethiopia are often living in orphanagesin Addis Ababa, an area free of malaria, at the time of theiradoption, but they may have lived in a malaria-endemicarea before their transfer to the orphanage. The prevalenceof asymptomatic malaria parasitemia among these childrenis not known.The StudyWe reviewed medical records of all children adopted fromEthiopia and seen at the University of Minnesota InternationalAdoption Clinic (Minneapolis, MN, USA) duringFebruary 2006–June 2011 for results of standard infectiousdisease screening tests recommended by the AmericanAcademy of Pediatrics: tuberculosis (by tuberculin skintest or, in children >5 years old, by interferon-g release assay);intestinal parasites (fecal testing for ova, parasites,and Giardia intestinalis antigen); hepatitis B or C virus;HIV; and syphilis (5). Children were screened for hepatitisA virus at the discretion of the physician seeing the patientAuthor affiliations: Children’s Hospital of Philadelphia,Philadelphia, Pennsylvania, USA (S.M. Adebo); Universityof Minnesota, Minneapolis, Minnesota, USA (J.K. Eckerle,M.E. Andrews, C.R. Howard, C.C. John); Indiana University,Indianapolis, Indiana, USA (C.C. John)DOI: http://dx.doi.org/10.3201/eid2107.141933and for malaria by blood smear or PCR if they met screeningcriteria (i.e., history of living in a malaria-endemic regionor a history of or current evidence of splenomegalyor hepatomegaly). The study was reviewed and approvedby the University of Minnesota Institutional Review Board.During the period studied, 255 international adopteesfrom Ethiopia were seen at the clinic. Adoptees’ mean ageat medical evaluation was 2.8 years (range 3.4 months–14.9years); 148 (58%) were female and 107 (41.9%) were male.All 255 children were asymptomatic for malaria, but 52met malaria screening criteria and were tested by peripheralblood smear (n = 24), PCR (n = 24), or both (n = 4). Ofthe 52 children, 7 (13.5%) had blood smear (2 children) orPCR (5 children) results positive for Plasmodium species.Table 1 outlines the sensitivity, specificity, and negativeand positive predictive values of medical history questionsand physical exam signs for asymptomatic malaria. The2 children with a positive blood smears had low parasitedensities (
- Page 3 and 4:
July 2015SynopsisOn the CoverMarian
- Page 5 and 6:
1240 Gastroenteritis OutbreaksCause
- Page 7 and 8:
SYNOPSISDisseminated Infections wit
- Page 9 and 10:
Disseminated Infections with Talaro
- Page 11 and 12:
Disseminated Infections with Talaro
- Page 13 and 14:
Macacine Herpesvirus 1 inLong-Taile
- Page 15 and 16:
Macacine Herpesvirus 1 in Macaques,
- Page 17 and 18:
Macacine Herpesvirus 1 in Macaques,
- Page 19:
Macacine Herpesvirus 1 in Macaques,
- Page 23:
Malaria among Young Infants, Africa
- Page 26 and 27:
RESEARCHFigure 3. Dynamics of 19-kD
- Page 28 and 29:
Transdermal Diagnosis of MalariaUsi
- Page 30 and 31:
RESEARCHFigure 2. A) Acoustic trace
- Page 32 and 33:
RESEARCHof malaria-infected mosquit
- Page 34 and 35:
Lack of Transmission amongClose Con
- Page 36 and 37:
RESEARCH(IFA) and microneutralizati
- Page 38 and 39:
RESEARCHoropharyngeal, and serum sa
- Page 40 and 41:
RESEARCH6. Assiri A, McGeer A, Perl
- Page 42 and 43:
RESEARCHadvanced genomic sequencing
- Page 44 and 45:
RESEARCHTable 2. Next-generation se
- Page 46 and 47:
RESEARCHTable 3. Mutation analysis
- Page 48 and 49:
RESEARCHReferences1. Baize S, Panne
- Page 50 and 51:
Parechovirus Genotype 3 Outbreakamo
- Page 52 and 53:
RESEARCHFigure 1. Venn diagramshowi
- Page 54 and 55:
RESEARCHTable 2. HPeV testing of sp
- Page 56 and 57:
RESEARCHFigure 5. Distribution of h
- Page 58 and 59:
RESEARCHReferences1. Selvarangan R,
- Page 60 and 61:
RESEARCHthe left lobe was sampled b
- Page 62 and 63:
RESEARCHTable 2. Middle East respir
- Page 64 and 65:
RESEARCHseroprevalence in domestic
- Page 66 and 67:
RESEARCHmeasure their current surve
- Page 68 and 69:
RESEARCHTable 2. States with labora
- Page 70 and 71:
RESEARCHFigure 2. Comparison of sur
- Page 72 and 73:
RESEARCH9. Centers for Disease Cont
- Page 74 and 75:
RESEARCHthe analyses. Cases in pers
- Page 76 and 77:
RESEARCHTable 3. Sampling results (
- Page 78 and 79:
RESEARCHpresence of Legionella spp.
- Page 80 and 81:
Seroprevalence for Hepatitis Eand O
- Page 82 and 83: RESEARCHTable 1. Description of stu
- Page 84 and 85: RESEARCHTable 3. Crude and adjusted
- Page 86 and 87: RESEARCHrates by gender or HIV stat
- Page 88 and 89: RESEARCH25. Taha TE, Kumwenda N, Ka
- Page 90 and 91: POLICY REVIEWDutch Consensus Guidel
- Page 92 and 93: POLICY REVIEWTable 3. Comparison of
- Page 94 and 95: POLICY REVIEW6. Botelho-Nevers E, F
- Page 96 and 97: DISPATCHESFigure 1. Phylogenetic tr
- Page 98 and 99: DISPATCHESSevere Pediatric Adenovir
- Page 100 and 101: DISPATCHESTable 1. Demographics and
- Page 102 and 103: DISPATCHES13. Kim YJ, Hong JY, Lee
- Page 104 and 105: DISPATCHESTable. Alignment of resid
- Page 106 and 107: DISPATCHESFigure 2. Interaction of
- Page 108 and 109: DISPATCHESSchmallenberg Virus Recur
- Page 110 and 111: DISPATCHESFigure 2. Detection of Sc
- Page 112 and 113: DISPATCHESFigure 1. Histopathologic
- Page 114: DISPATCHESFigure 2. Detection of fo
- Page 117 and 118: Influenza Virus Strains in the Amer
- Page 119 and 120: Novel Arenavirus Isolates from Nama
- Page 121 and 122: Novel Arenaviruses, Southern Africa
- Page 123 and 124: Readability of Ebola Informationon
- Page 125 and 126: Readability of Ebola Information on
- Page 127 and 128: Patients under investigation for ME
- Page 129 and 130: Patients under investigation for ME
- Page 131: Wildlife Reservoir for Hepatitis E
- Page 135 and 136: Asymptomatic Malaria in Children fr
- Page 137 and 138: Bufavirus in Wild Shrews and Nonhum
- Page 139 and 140: Bufavirus in Wild Shrews and Nonhum
- Page 141 and 142: Range Expansion for Rat Lungworm in
- Page 143 and 144: Slow Clearance of Plasmodium falcip
- Page 145 and 146: Slow Clearance of Plasmodium falcip
- Page 147 and 148: Gastroenteritis Caused by Norovirus
- Page 149 and 150: Ebola Virus Stability on Surfaces a
- Page 151 and 152: Ebola Virus Stability on Surfaces a
- Page 153 and 154: Outbreak of Ciprofloxacin-Resistant
- Page 155 and 156: Outbreak of S. sonnei, South KoreaT
- Page 157 and 158: Rapidly Expanding Range of Highly P
- Page 159 and 160: Cluster of Ebola Virus Disease, Bon
- Page 161 and 162: Cluster of Ebola Virus Disease, Lib
- Page 163 and 164: ANOTHER DIMENSIONThe Past Is Never
- Page 165 and 166: Measles Epidemic, Boston, Massachus
- Page 167 and 168: LETTERSInfluenza A(H5N6)Virus Reass
- Page 169 and 170: LETTERSsystem (8 kb-span paired-end
- Page 171 and 172: LETTERS3. Van Hong N, Amambua-Ngwa
- Page 173 and 174: LETTERSTable. Prevalence of Bartone
- Page 175 and 176: LETTERSavian influenza A(H5N1) viru
- Page 177 and 178: LETTERSprovinces and a total of 200
- Page 179 and 180: LETTERS7. Manian FA. Bloodstream in
- Page 181 and 182: LETTERSforward projections. N Engl
- Page 183 and 184:
LETTERS3. Guindon S, Gascuel OA. Si
- Page 185 and 186:
BOOKS AND MEDIAin the port cities o
- Page 187 and 188:
ABOUT THE COVERNorth was not intere
- Page 189 and 190:
Earning CME CreditTo obtain credit,
- Page 191:
Emerging Infectious Diseases is a p