Detection and Expression of Biosynthetic Genes in Actinobacteria ...

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_____________________________________________________________________________________Zotchev, S., Haugan, K., Sekurova, O., Sletta, H., Ellingsen, T.E. and Valla, S. (2000).Identification of a gene cluster for antibacterial polyketide-derived antibiotic biosynthesisin the nystatin producer Streptomyces noursei ATCC 11455. Microbiology 146:611-619.____________________________________________________________________________________167
_____________________________________________________________________________________Iwai, Y and Omura, S. (1982). Culture conditions for screening of new antibiotics.J. Antibiot. 35:123-141.Jacobsen, J.R., Hutchinson, C.R., Cane, D.E and Khosla, C. (1997). Precursor-directedbiosynthesis of erythromycin analogs by an engineered polyketide synthase. Science277:367-369.James, P.D.A., Edwards, C and Dawson, M. (1991). The effects of temperature, pH andgrowth rate on secondary metabolism in Streptomyces thermoviolaceus grown in achemostat. J. Gen. Microbiol. 137:1715-1720.Jensen, P.R and Fenical, W. (1994). Strategies for the discovery of secondary metabolitesfrom marine bacteria: ecological perspectives. Annu. Rev. Microbiol. 48:559-84.Jermini, M.F.G and Demain, A.L. (1989). Solid state fermentation for cephalosporinproduction by streptomyces clavuligerus and cephalosporin acremonium. Experimentia45:1061-1065.Jia, S., Chen, G., Kahar, P., Choi, D-B and Okabe, M.(1999). Effect of soybean oil onoxygen transfer in the production of tetracycline with an airlift bioreactor.J. Biosc. Bioeng. 87(6):825-827.Jiang, C and Xu, L. (1993). Actinomycete diversity in unusual habitats. Actinomycetes4(2):47-57.Jin-Cheol, Y., Han, J-M and Sohng, J.K. (1999). Expression of orf7(oxiIII) as Dtdpglucose4,6-dehydratase gene cloned from Streptomyces antibioticus Tü99 andbiochemical characteristics of expressed protein. J. Microbiol. Biotechnol. 9(2):206-212.Johnson, D.A. and Liu, H.W. (1998). Mechanisms and pathways from recent deoxysugarbiosynthesis research. Curr. Opin. Chem. Biol. 2:642-649.Johnson, D.A. and Liu, H.W. “Deoxysugars: occurrence, genetics, and mechanisms ofbiosynthesis.” Comprehensive natural products chemistry. Ed. Pinto, B.M. Oxford. UK:Elsevier Science Ltd, 1999. 311-365.Jones, A. and Westlake, D. W. S. (1974). Regulation of chloramphenicol synthesis inStreptomyces sp. 3022a. Properties of arylamine synthetase, an enzyme involved inantibiotic synthesis. Can. J. Microbiol. 20:1599-1611.Jones, A.M and Porter, M.A. (1998). Vegetable oils in fermentation: beneficial effects oflow-level supplementation. J. Ind. Microbiol. Biotechnol. 21:203-207._____________________________________________________________________________________161
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BERVANAKIS, G.Chapter 1: INTRODUCTI
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BERVANAKIS, G.Chapter 2: MATERIALS
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BERVANAKIS, G.Chapter 3: RESULTSSec
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BERVANAKIS, G.Chapter 4: DISCUSSION
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