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Detection and Expression of Biosynthetic Genes in Actinobacteria ...

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BERVANAKIS, G.Chapter 1: INTRODUCTIONTable 8: DNA Probes used <strong>in</strong> the detection <strong>of</strong> SMBG <strong>in</strong> Act<strong>in</strong>obacteria spp.SMBG Act<strong>in</strong>obacteria Compound Probe ReferenceGroupClassSaccharopolyspora spp. Macrolide eryPKS, ermE Stanzak et al., 1990Saccharopolyspora Macrolide ermE Cortes et al., 1990erythraeaS. longispor<strong>of</strong>lavns Polyether AT DEBS3 Cooper et al., 1992S .cyaneogriseus Macrolide AT Gibbons et al., 1992S. FR-008 sp. Polyene Macrolide pab, eryPKS Hu et al., 1994S. cori<strong>of</strong>aciens Macrolide 5c Kuczek et al., 1994S. antibioticus Macrolide eryA Swan et al., 1994S. hygroscopicus Macrolide eryA Schwecke et al., 1995S. caelestis Macrolide PKS Kakavas et al., 1997S. sp.MA6548 Macrolide fkbD Motamedi et al., 1997S. hygroscopicus Macrolide m5 eryPKS Ruan et al., 1997S. sp. MA6548 Macrolide fkbA Motamedi et al, 1997S. venezuelae Macrolide type I PKS(HP) Xue et al., 1998S. natalensis Polyene Macrolide rapPKS Aparicio et al., 1999S. noursei Polyene Macrolide KS-ACP Brautaset et al., 2000AmycolatopsisAnsamyc<strong>in</strong> rifR Doi-Katayama et al., 2000mediterrianae S699S. antibioticus Macrolide oleP Shah et al., 2000M. megalomicea Macrolide KS2 eryDEBS Volchegursky et al., 2000S. hygroscopicus var. Macrolide rapP, fkbM Wu et al., 2000ascomyceticusSaccharopolysporasp<strong>in</strong>osaMacrolide KS Waldron et al., 2001Act<strong>in</strong>osynnema pretiosum Ansamyc<strong>in</strong> rifK & AHBA Yu et al., 2002Streptomyces spp. Isochromanequ<strong>in</strong>one actI & actIII Malpartida et al., 1987Anthracycl<strong>in</strong>esType I Polyketide SynthaseType II Polyketide SynthaseS. arenae Isochromanequ<strong>in</strong>one actI Brünker et al., 1999S. c<strong>in</strong>namonensis Polyether actI & actIII Arrowsmith et al., 1992S. curacoi Curamyc<strong>in</strong> actI Bergh & Uhlén, 1992S. murayamaensis Angucycl<strong>in</strong>e actI Gould et al., 1998Act<strong>in</strong>omadura hibisca Angucycl<strong>in</strong>e KS & AT* Dairi et al., 1997Act<strong>in</strong>omaduraAngucycl<strong>in</strong>e KS & AT Dairi et al., 1999verrucososporaSaccharopolyspora Glycopeptide actI Le Gouill et al., 1993hirsuta 367Kibdelsporangium Glycopeptide actI & actIII Piecq et al., 1994aridumS .rose<strong>of</strong>ulvus Isochromanequ<strong>in</strong>one actI & actIII Bibb et al., 1994S. griseus Benzoisochromanes actI & actIII Yu et al., 1994S. peucetius Anthracycl<strong>in</strong>e tcmKLN Grimm et al., 1994S. venezuelae Angucycl<strong>in</strong>e actI & actIII Han et al., 1994S. sp. Stra<strong>in</strong> C5 Anthracycl<strong>in</strong>e actI & actIII, Ye et al., 1994PKRS. fradiae Tü2717 Angucycl<strong>in</strong>e tcmKC Decker & Haag, 1995S. nogalater Anthracycl<strong>in</strong>e actI & acm Ylihonko et al., 1996S. violaceoruber Tü22 Benzoisochromanes actI & actIII Sherman et al., 1989S. olivaceus Tü2353 Napthacenequ<strong>in</strong>ones tcmG Rafanan et al., 2001S. nogalater Anthracycl<strong>in</strong>e nogPKS Torkkell et al., 2001_____________________________________________________________________31

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