Detection and Expression of Biosynthetic Genes in Actinobacteria ...

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_____________________________________________________________________________________Neilands, J.B. (1995). Siderophores: structure and function of microbial iron transportcompounds. J. Biol. Chem. 270:26723-26726.Neves, A.A., Vieira, L.M. and Menezes, J.C. (2001). Effects of preculture variability onclavulanic acid fermentation. Biotech. Bioeng. 72(6):628-633.Nicholson, T.P., Rudd, B.A.M., Dawson, M., Lazarus, C.M., Simpson, T.J and Cox, R.J.(2001). Design and utility of oligonucleotide gene probes for fungal polyketidesynthases. Chem. Biol. 8:157-178.Niebla-Perez, A and Wellington, E.M.H. “Development of a PCR system for thedetection of β-lactam antibiotic producer actinomycetes in soil.” 5 th Internationalsymposium on biology of actinomycetes. Abstracts Book. Beijing, China, 1997. 6P23.Niebla-Perez, A., Egan, S., del Sol, R., Gonzalez, I., Gonzalez, L., Wellington, E.M.Hand Vallin., C. (1999). Amplification by PCR and comparative sequence analysis of thegene coding for Isopenicillin N synthase in Streptomyces sulfonofacies. Hellenic societyof biological sciences. Proceedings of the 11th ISBA, Crete. Greece. 190.O’Donnell, A.G. “Recognition of novel actinomycetes.” Actinomycetes inbiotechnology. London, UK: Academic Press Ltd, 1988. 69-88.Ogawara, H. (1996). Structure and evolution of β-lactamase genes from Streptomyces.Actinomycetol. 10(2):104-111.Ohno, H., Yoshida, Y., Takahashi, Y. and Ōmura, S. (1980). Improvement of theproductivity of elasnin, a specific elastase inhibitor, by Streptomyces nohoritoensis KM-2753. J. Antibiot. 33:474-479.Okuta, A., Ohnishi, K and Harayama, S. (1998). PCR isolation of catechol 2,3-dioxygenase gene fragments from environmental samples and their assembly intofunctional genes. Gene. 212:221-228Ōmura, S and Tanaka, Y. “Control of ammonium ion level in antibiotic fermentation”Biological, Biochemical, and Biomedical Aspects of Actinomycetes Ed. Ortiz-Ortiz, L.,Bojalil, L. F., and Yakoleff, V. Orlando, FL, Academic Press, 1984. 367-378.Ōmura, S. (1986). Philosophy of new drug discovery. Microbiol. Rev. 50(3):259-279.Ooijkaas, L.P., Weber, F.J., Buitelaar, R.M., Tramper, J and Rinzema, A. (2000). Definedmedia and inert supports: their potential as solid-state fermentation production systems.Trends Biotechnol. 18:356-360.Ortona, E., Margutti, P., De Luca, A., Peters, S.E., Wakefield, A.E., Tamburrini, E.,Mencarini, P., Visconti, E and Siracusano, A. (1996). Non specific PCR products using_____________________________________________________________________________________168
_____________________________________________________________________________________rat-derived Pneumocystis carinii dihydrofolate reductase gene-specific primers in DNAamplification of human respiratory samples. Mol. Cell. Probes. 10:187-190.Osada, H. (1995). Fascinating bioactive compounds from actinomycetes. Actinomycetol.9(2): 254-262._____________________________________________________________________________________169
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BERVANAKIS, G.Chapter 1: INTRODUCTI
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BERVANAKIS, G.Chapter 2: MATERIALS
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BERVANAKIS, G.Chapter 3: RESULTSSec
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BERVANAKIS, G.Chapter 4: DISCUSSION
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