th  - 1988 - 51st ENC Conference

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MULTIVOLUME SELECTIVE SPECTROSCOPY, DEUTERIUM IMAGING AND. 13C-NMR
~ED 10:30 I AS TOOLS FOR THE STUDY OF IN VIVO METABOLISM
Joachim Seelig , S. MUller, J. Link, and S. Cerdan, Biocenter, University of Basel,
Basel, Switzerland
The main problem of in vivo spectroscopy is the precise selection of the region of
interest with sufficient sensitivity. Image-guided, simultaneous sgectroscopy of
multiple volumes is possible via the application of frequency selective pulses
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composed of several excitation frequencies. The feasibility of multivolume P-NMR
spectroscopy will be demonstrated for phantoms and for human heart. The availability
of a rampable magnet allows routine MR-Imaging at 1.5 T and MR-Spectroscopy at 2 T
with only 20 min intervals. Deuterium MR-Imaging will be introduced as a new method
for contrast enhancement and flow. The application of 13C-NMR to the in vivo study
of liver metabolism of rat will be discussed.
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