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th  - 1988 - 51st ENC Conference

th  - 1988 - 51st ENC Conference

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WED ii:00 J<br />

HUMAN IN VIVO SPECTROSCOPY AT 4.0T<br />

Dietmar Hentschel, Jurgen Vetter, Ralf Ladebeck, and Michael J. Albright*<br />

Siemens AG, D-8520 Erlangen, FDG<br />

A 4 T six-coil SCM wi<strong>th</strong> a warm bore of 1.25 m diameter was designed<br />

wi<strong>th</strong> high homogeneity for use wi<strong>th</strong> in vivo spectroscopy. Computer optimized<br />

design was used to correct terms up to 10<strong>th</strong> order. The magnet can be ramped<br />

to 4 T in 1 hour. The rated current is 376 A, and <strong>th</strong>e stored field energy is 39<br />

MJ. The field drift is less <strong>th</strong>an 3.6 x 10-e/h, and bare homogeneity of 100 ppm<br />

can be corrected to less <strong>th</strong>an +2.5 ppm for a 50 cm dsv. The total magnet<br />

weight is 10.6 tons.<br />

Increased spectral dispersion will be shown by comparison wi<strong>th</strong> 2 T<br />

spectra. Human in vivo 31p spectra at 4 T show resolution of <strong>th</strong>e different<br />

PDE resonances, and, on some spectra, separation of <strong>th</strong>e dinucleotides and<br />

nucleoside diphosphosugars upfield of <strong>th</strong>e (z-ATP peak.<br />

High field RF penetration will be demonstrated wi<strong>th</strong> a 1H image at 4 T.<br />

56

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