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Microbiology, 2021

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Review Questions 554<br />

CHAPTER 14<br />

Antimicrobial Drugs 557<br />

Introduction 557<br />

14.1 History of Chemotherapy and Antimicrobial Discovery 558<br />

14.2 Fundamentals of Antimicrobial Chemotherapy 562<br />

14.3 Mechanisms of Antibacterial Drugs 566<br />

14.4 Mechanisms of Other Antimicrobial Drugs 580<br />

14.5 Drug Resistance 591<br />

14.6 Testing the Effectiveness of Antimicrobials 597<br />

14.7 Current Strategies for Antimicrobial Discovery 601<br />

Summary 604<br />

Review Questions 606<br />

CHAPTER 15<br />

Microbial Mechanisms of Pathogenicity 611<br />

Introduction 611<br />

15.1 Characteristics of Infectious Disease 612<br />

15.2 How Pathogens Cause Disease 618<br />

15.3 Virulence Factors of Bacterial and Viral Pathogens 629<br />

15.4 Virulence Factors of Eukaryotic Pathogens 643<br />

Summary 646<br />

Review Questions 647<br />

CHAPTER 16<br />

Disease and Epidemiology 651<br />

Introduction 651<br />

16.1 The Language of Epidemiologists 652<br />

16.2 Tracking Infectious Diseases 657<br />

16.3 Modes of Disease Transmission 663<br />

16.4 Global Public Health 673<br />

Summary 677<br />

Review Questions 678<br />

CHAPTER 17<br />

Innate Nonspecific Host Defenses 683<br />

Introduction 683<br />

17.1 Physical Defenses 684<br />

17.2 Chemical Defenses 691<br />

17.3 Cellular Defenses 700<br />

17.4 Pathogen Recognition and Phagocytosis 708<br />

17.5 Inflammation and Fever 713<br />

Summary 719<br />

Review Questions 720<br />

CHAPTER 18<br />

Adaptive Specific Host Defenses 725<br />

Introduction 725<br />

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