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Microbiology, 2021

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22 • Review Questions 941<br />

18. Which of the following is caused by infections<br />

by bread molds?<br />

A. mucormycosis<br />

B. coccidioidomycosis<br />

C. cryptococcosis<br />

D. Pneumocystis pneumonia<br />

19. In the United States, most histoplasmosis cases<br />

occur<br />

A. in the Pacific northwest.<br />

B. in the desert southwest.<br />

C. in the Mississippi river valley.<br />

D. in Colorado river valley.<br />

20. Which of the following infections can be<br />

diagnosed using a skin test similar to the<br />

tuberculin test?<br />

A. histoplasmosis<br />

B. cryptococcosis<br />

C. blastomycosis<br />

D. aspergillosis<br />

Fill in the Blank<br />

21. Unattached microbes are moved from the lungs<br />

to the epiglottis by the _______ effect.<br />

22. Many bacterial pathogens produce _______ to<br />

evade phagocytosis.<br />

23. The main type of antibody in the mucous<br />

membrane defenses is _______.<br />

24. _______ results from an inflammation of the<br />

“voice box.”<br />

25. _______ phagocytize potential pathogens in the<br />

lower lung.<br />

26. Calcified lesions called _______ form in the<br />

lungs of patients with TB.<br />

27. An inflammation of the middle ear is called<br />

_______.<br />

28. The _______ is used to serologically identify<br />

Streptococcus pneumoniae isolates.<br />

29. _______ is a zoonotic infection that can be<br />

contracted by people who handle birds.<br />

30. The main virulence factor involved in scarlet<br />

fever is the _______.<br />

31. The _______ virus is responsible for causing<br />

German measles.<br />

Short Answer<br />

41. Explain why the lower respiratory tract is<br />

essentially sterile.<br />

42. Explain why pneumonia is often a lifethreatening<br />

disease.<br />

43. Name three bacteria that commonly cause<br />

pneumonia. Which is the most common cause?<br />

44. How does smoking make an individual more<br />

susceptible to infections?<br />

45. How does the diphtheria pathogen form a<br />

pseudomembrane?<br />

32. A(n) _______ is an uncontrolled positive<br />

feedback loop between cytokines and<br />

leucocytes.<br />

33. In cases of shingles, the antiviral drug _______<br />

may be prescribed.<br />

34. The slow accumulation of genetic changes to an<br />

influenza virus over time is referred to as<br />

_______.<br />

35. The _______ vaccine is effective in controlling<br />

both measles and rubella.<br />

36. In coccidioidomycosis, _______ containing<br />

many endospores form in the lungs.<br />

37. In cryptococcosis, the main fungal virulence<br />

factor is the _______, which helps the pathogen<br />

avoid phagocytosis.<br />

38. In some mycoses, fungal balls called _______<br />

form in the lungs<br />

39. Most US cases of coccidioidomycosis occur in<br />

_______.<br />

40. Coccidioidomycosis may develop when<br />

Coccidioides immitis _______ are inhaled.<br />

46. Since we all have experienced many colds in our<br />

lifetime, why are we not resistant to future<br />

infections?<br />

47. Which pulmonary fungal infection is most likely<br />

to be confused with tuberculosis? How can we<br />

discriminate between these two types of<br />

infection?<br />

48. Compare and contrast aspergillosis and<br />

mucormycosis.

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