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Microbiology, 2021

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CHAPTER 17<br />

Innate Nonspecific Host<br />

Defenses<br />

Figure 17.1 Varicella, or chickenpox, is caused by the highly contagious varicella-zoster virus. The characteristic<br />

rash seen here is partly a result of inflammation associated with the body’s immune response to the virus.<br />

Inflammation is a response mechanism of innate immunity that helps the body fight off a wide range of infections.<br />

(credit: John Noble / CDC; Public Domain)<br />

Chapter Outline<br />

17.1 Physical Defenses<br />

17.2 Chemical Defenses<br />

17.3 Cellular Defenses<br />

17.4 Pathogen Recognition and Phagocytosis<br />

17.5 Inflammation and Fever<br />

INTRODUCTION Despite relatively constant exposure to pathogenic microbes in the environment, humans

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