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Lead Toxicity in Mute Swans

LEAD TOXICITY IN MUTE SWANS Cygnus olor (Gmelin). By JOHN O'HALLORAN A thesis submitted to the National University of Ireland in candidature for the degree of Doctor of Philosophy September 1987

LEAD TOXICITY IN MUTE SWANS
Cygnus olor (Gmelin).
By
JOHN O'HALLORAN
A thesis submitted to the National University of Ireland
in candidature for the degree of Doctor of Philosophy
September 1987

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SUMMARY<br />

Reference levels of some biochemical and haematological parameters<br />

were determ<strong>in</strong>ed for <strong>Mute</strong> swans (Cygnus olor Gmel<strong>in</strong>).<br />

Two physiological<br />

states, moult<strong>in</strong>g and immaturity, were identified as factors which<br />

broadened the reference levels.<br />

Blood parameters of six acutely<br />

lead-poisoned swans were determ<strong>in</strong>ed and compared with the reference<br />

distribution. Protoporphyr<strong>in</strong> IX, cholesterol and two serum enzymes,<br />

lactate dehydrogenase (LDH) and aspartate am<strong>in</strong>otransferase (AST), were<br />

found to <strong>in</strong>crease <strong>in</strong> lead poisoned birds.<br />

Concentrations of<br />

haemoglob<strong>in</strong>, mean cell haemoglob<strong>in</strong> concentration and haematocrit<br />

<strong>in</strong>dicated severe hypochromic anaemia <strong>in</strong> birds with acute lead<br />

poison<strong>in</strong>g.<br />

The diagnostic value and <strong>in</strong>terpretation of reference values<br />

is discussed.<br />

- 86 -<br />

I<br />

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