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Scientific and Technical Aerospace Reports Volume 39 April 6, 2001

Scientific and Technical Aerospace Reports Volume 39 April 6, 2001

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(EDB) to measure the thermophoretic force on single microsphere particles. In an EDB a vertical dc field cancels the gravitational<br />

force on a particle <strong>and</strong> the thermophoretic force is measured in terms of this dc voltage. Another superimposed ac field keeps the<br />

levitated particle stable. However, there are two challenges in using an EDB to measure thermophoretic forces. One is to keep<br />

trapped particles stable at the very low ac voltage that is necessary to avoid gas glow discharge at reduced pressure. The other is<br />

to determine the size <strong>and</strong> mass of the single particles, especially non-spherical ones, accurately in order to interpret the data. Particle<br />

stability was improved by adding two independent dc fields in the radial direction with a new octuple double-ring design for<br />

the EDB electrodes, as shown. A conventional double-ring EDB was modified by splitting each ring into four equal electrically<br />

independent sections. Three dc sources were combined such that eight potentials were applied to the eight sections of the electrodes.<br />

An additional ac voltage was superimposed on each ring section as in the conventional double-ring EDB. The resulting<br />

electric field has dc components in the x, y <strong>and</strong> z-directions, which can be controlled independently by the three dc supplies. The<br />

z component is equivalent to the dc field in the conventional EDB <strong>and</strong> can be used to balance <strong>and</strong> measure any vertical force such<br />

as gravity. The x <strong>and</strong> y fields can be used to suppress radial oscillations of the trapped particles that arise due to gas convection<br />

or distortion of the electric field by the view ports in the chamber walls. The aerodynamic size of the trapped particles can be determined<br />

by a stable oscillation technique that we have developed previously. This technique involves partially balancing the particle<br />

against gravity <strong>and</strong> allowing the particle to oscillate in the ac field. The oscillation trajectories are recorded with a fast linescan<br />

camera <strong>and</strong> are fit to the solutions of the particle equation of motion. With the aid of a video microscopy system the shape <strong>and</strong><br />

orientation of the particle with respect to the electric field is determined. The geometric dimensions <strong>and</strong> mass of the particles can<br />

be calculated from the aerodynamic size, the shape <strong>and</strong> the orientation with the knowledge of particle density. Using this method<br />

we were able to determine the size <strong>and</strong> mass of PSL particles of two- <strong>and</strong> three-sphere aggregates. We have measured the thermophoretic<br />

force on these PSL aggregates in nitrogen gas in the Knudsen regime. The thermophoretic force data, as well as particle<br />

shapes <strong>and</strong> equivalent volume diameters, are shown. At a Knudsen number of one, the normalized thermophoretic force on the<br />

two- <strong>and</strong> three-sphere aggregate is, respectively, 23% <strong>and</strong> 10% greater than that on a single sphere. This implies that two- <strong>and</strong><br />

three-sphere aggregates drift faster due to thermophoresis than single spheres. Once aggregate particles form there may be a positive<br />

feedback mechanism for more aggregation due to the higher mobility of the aggregate spheres.<br />

Author (revised)<br />

Thermophoresis; Particle Motion; Spheres; Transport Properties; Trapped Particles; Convection; Direct Current; Electric<br />

Fields; Microparticles<br />

<strong>2001</strong>0024966 Michigan Univ., Biomedical Engineering Dept., Ann Arbor, MI USA<br />

Capillary Instabilities in the Microgravity Environment<br />

Grotberg, James B., Michigan Univ., USA; Benintendi, Steven W., Michigan Univ., USA; Halpern, David, Alabama Univ., USA;<br />

Proceedings of the Fifth Microgravity Fluid Physics <strong>and</strong> Transport Phenomena Conference; December 2000, pp. 1286-1288; In<br />

English; See also <strong>2001</strong>0024890; No Copyright; Abstract Only; Available from CASI only as part of the entire parent document<br />

The lung is comprised of a network of bifurcating airway tubes which are coated with a thin viscous film. Often times, especially<br />

in the case of disease, the liquid film can form a meniscus which fills the whole tube, thus obstructing airflow. The formation<br />

of the liquid meniscus is due to capillary driven instabilities which can arise in the lining, causing the lining to close up. In addition,<br />

airflow can also be obstructed if the airway tube collapses in on itself. This occurs when the elastic forces of the tube are not large<br />

enough to sustain the negative fluid pressures inside the tube caused by surface-tension, <strong>and</strong> the tube collapses. In both cases, the<br />

instability is dependent on the surface tension of the liquid lining. In normal gravity, airway closure occurs at the end of a forced<br />

expiration as a normal event even in health lungs. The amount of air remaining in the lungs when this happens is called the closing<br />

volume. Fortunately, because of gravity the closure process tends to occur in the lower regions of the lung, due to the weight of<br />

the tissue above. In microgravity, it is likely that closure occurs more homogeneously <strong>and</strong> thus exposes the lung to potential risks.<br />

Once the airway is closed, it then must be reopened, usually this is done by taking a deep breath which forces the liquid plug to<br />

move <strong>and</strong> deposit its volume onto a trailing film. There are other important issues regarding airway closure which relate to pulmonary<br />

disease. For example, premature babies, whose lungs have not developed sufficient surfactant to maintain the surface tension<br />

of the lung at a sufficiently low level for healthy functioning, are especially predisposed to problems caused by airway closure.<br />

In such cases, the patients are sometimes put on high frequency ventilation machines to improve oxygenation. The frequency of<br />

the breathing cycle, as well as the tidal volume, are two control parameters at the disposal of the clinician. Little is known, however,<br />

of the effect that these two parameters can have on the occurrence of airway closure. Indeed, if airways can be kept open by using<br />

some given imposed frequency, then this would important in the treatment of such patients. In addition to medical applications,<br />

the general topic of multiphase flows over flexible boundaries is important for a number of technical fields including flows in<br />

poroelastic media. We have investigated the closure phenomenon in flexible tubes in the past. Recently, we developed a theoretical<br />

model of perturbed airway closure to study the effects of forced oscillatory air flow on the closure phenomenon. It consists of a<br />

single rigid tube coated with a thin viscous layer. to examine the stability of the layer, we derived an evolution equation for the<br />

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