POSTER ABSTRACTS - ISAKOS

with successful result, while 67.3% (35) of them
retained their preoperative activity level.
Risk factors for failure of meniscus repair are
chronicity of injury, location of tear more than 3
mm from the meniscosynovial junction and
meniscus side (medial). At all events, the Fast-
FixTM absorbable anchor seems to be a very
promising all-inside meniscus repair device
because of its efficacy ,safety and ease to use.
•E-poster #739
The Relationship Between Complete Discoid
Lateral Meniscus and Cartilage Degeneration:
A Cadaver Study
Yuki Kato, Tokyo, JAPAN, Presenter
Midori Oshida, Tokyo, JAPAN
Shin Aizawa, Tokyo, JAPAN
Akiyoshi Saito, Tokyo, JAPAN
Junnosuke Ryu, Tokyo, JAPAN
Nihon University, Tokyo, JAPAN
[Objective] The prevalence and tear morphology
of complete discoid lateral meniscus (CDLM) and
its relationship to osteoarthritic (OA) changes
were investigated using cadavers.
[Subjects] The authors examined 577 knees (311
male and 266 female) of cadavers used for
autopsy practice at Nihon University between
1991 and 2003. Twenty one knees with CDLM
served as subjects.
[Methods] In 21 knees with CDLM, the incidence
and morphology of tear and the severity of OA
changes were investigated. The average age of the
cadavers was 80.7±7.3 years (range: 65 to 98
years). The P-F joint (patellar surface of the femur
and patellar groove) and F-T joint (femoral
condyle and tibial plateau) were macroscopically
assessed for OA changes, and severity was
classified into the following four grades: 0,
normal; I (mild) cartilage roughness, fibrosis or
shallow abrasion; II (moderate) regional full-layer
cartilage loss or partial bone exposure; and III
(severe) extensive subchondral bone exposure.
[Results] The incidence of CDLM was 2.9% (9/311
knees) for men and 4.5% (12/266 knees) for
women; there was no statistically significant
difference between the sexes. Overall incidence of
CDLM was 3.6% (21/577 knees). Torn CDLM was
seen in six knees (28.6%), and the mode of tear
was transverse in five knees and complex in one
knee. No OA change was seen in four knees; No F-
T OA was seen in six knees with P-F OA; medial
OA was seen in nine knees; and lateral OA was
seen in two knees. The incidence of OA on the
lateral tibial plateau was significantly higher for
torn CDLM (p=0.004).
E-poster #740
Biochemical Changes in Synovial Fluid of the
Contra-Lateral Knee in Unilateral Focal Osteochondral
Defects with or without Treatment
Hakan Ozsoy, Ankara, TURKEY, Presenter
Semih Aydogdu, Izmir, TURKEY
Dilek TaskIRAN, Izmir, TURKEY
Murat Sezak, Izmir, TURKEY
Arzu Ozsoy, Ankara, TURKEY
Fikri Oztop, Izmir, TURKEY
Ege University Faculty of Medicine, Izmir, TURKEY
Purpose: In order to disclose possible
involvement of contra-lateral knee, in focal
osteochondral defects with or without treatment
on the other side, we analyzed early biochemical
changes in the synovial fluid samples of both
osteochodral-defected (right) and contra-lateral
(left) knees in rabbits.
Method: A 3.5x4mm tubular osteochondral defect
was created on the right medial femoral condyles
of 51 adult white rabbits. In 18 rabbits, (control
group (CG)) the defects were left alone. In 15
rabbits, (early treatment group (ETG)), defects
were treated by an osteoperiosteal graft, 7 to 15
days after the index procedure. In 18 rabbits, (the
late treatment group (LTG)), defects were grafted
at 12th weeks. The rabbits were followed-up to 24
weeks. Synovial fluid samples of both right and
left (unoperated) knees were collected regularly
(0, 1, 4, 8, 12, 18, 24th weeks) and proteoglycan
fragments (PF), total collagen (TC) and
collagenase (MMP-1) levels were measured. For
statistical analysis, ANOVA and post-hoc tests
were used.
Results: In CG, all markers displayed a significant
increase in the operated/right knee during whole
study period, which indicates an ongoing
degenerative process. Unoperated/left knee levels
also displayed a parallel, but statistically
insignificant increase.
In ETG; biochemical markers of operated knees
displayed a faster recovery to normal values after
grafting. Unoperated knee values never displayed
an increase probably related to early intervention.
In LTG, all markers displayed an increase until
treatment (12th week), and then some decrease;
but never reached normal values in most of
parameters. Unoperated knee values also