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POSTER ABSTRACTS - ISAKOS

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Result : The mean Lysholm knee score was 72.9<br />

points (range 48 to 99) at the latest follow-up. No<br />

statistically significant difference was found in<br />

Lysholm knee scores among the groups.<br />

Radiographic development of osteoarthritis was<br />

seen in 9.1% of the patients in Group 1, in 14.0%<br />

of Group II, in 25.0% of Group III, and in 28.2% of<br />

Group IV after 5 years. After 7 years, osteoarthritis<br />

increased to 18.2% of Group I patients, 29.1% of<br />

Group II, 46.4 % of Group III, and 54.5% of Group<br />

IV. There was statistically significant difference in<br />

radiographic evaluation among the groups.<br />

Conclusion : The development of osteoarthritis<br />

after total menisectomy was highly observed in<br />

cases involving the medial meniscus with ACL<br />

injury. To a lesser extent it was also seen, in order<br />

of incidence, in cases involving the discoid<br />

meniscus, the lateral meniscus, and the medial<br />

meniscus.<br />

E-poster #745<br />

Clinical Results and MRI Findings After<br />

Collagen Meniscus Implant (CMI)<br />

Paolo Bulgheroni, Varese, ITALY, Presenter<br />

Mario Ronga, Varese, ITALY<br />

Federico A. Grassi, Varese, ITALY<br />

Eugenio Genovese, Varese, ITALY<br />

Paolo Cherubino, Varese, ITALY<br />

Dipartimento di Ortopedia e Traumatologia,<br />

Varese, ITALY<br />

Aim: To report clinical results and MRI findings<br />

observed in 50 patients, who underwent collagen<br />

meniscus implant (CMI) between March 2001 and<br />

June 2003.<br />

Methods and materials: Fifty patients, who were<br />

affected by irreparable meniscal lesions or had<br />

previously undergone partial medial<br />

meniscectomy, were arthroscopically treated with<br />

CMI, a tissue engineering technique designed to<br />

promote meniscal regeneration. Average age at<br />

the time of surgery was 38.4 years. The average<br />

size of the lesion/defect was 4.3 cm. Additional<br />

procedures included 16 ACL reconstruction, 8<br />

high tibial osteotomy and 2 autologous<br />

chondrocyte implantation. All knees were<br />

evaluated according to the Lysholm II and Tegner<br />

activity scales. MRI (FSE Fat-Sat T2, SE T1, GRE<br />

T2) was performed 6, 12 and 24 months<br />

postoperatively. Six arthroscopic examinations of<br />

the implant were performed at different times (6<br />

to 16 months postoperatively).<br />

Results: Postoperative complications included<br />

saphenus neuroapraxia in 3 patients and CMI<br />

rupture in 1 patient who presented persistent<br />

knee swelling. Follow up averaged 15.7 months,<br />

with a minimum of 6 months. At most recent<br />

evaluation, 46 patients showed improvement of<br />

the clinical scores. MRI was useful to document<br />

healing of CMI to the meniscal stump and<br />

parameniscus, followed by tissue invasion and<br />

ingrowth inside the scaffold. A progression toward<br />

a more homogeneous signal was detected in the<br />

implants with a two-year follow-up. At second<br />

arthroscopic look, free fragments of the implant<br />

were observed in the knee of the patient, who<br />

suffered CMI rupture. In another patient, partial<br />

resorption of CMI was observed at the posterior<br />

horn. The remaining four arthroscopic<br />

examinations demonstrated regeneration of<br />

meniscal-like tissue with healing of the implants<br />

to the parameniscus and to the residual meniscal<br />

stump; good consistency and stability was<br />

detected by probing.<br />

Conclusions: Clinical results achieved with CMI<br />

are promising, once correct indications are<br />

respected and patients are compliant with<br />

rehabilitation program. MRI demonstrated to be<br />

an effective tool for monitoring the evolution of<br />

the implant and showed good correlation with<br />

clinical outcomes and arthroscopic findings at<br />

follow up.<br />

E-poster #746<br />

All-Inside Meniscus Suture: A New Technique<br />

Graeme Campbell Brown, AUSTRALIA, Presenter<br />

St John of God Hospital, Geelong, Victoria,<br />

AUSTRALIA<br />

The indications for meniscal tears have become<br />

better defined over recent years. The surgical<br />

options for a meniscal repair include open, insideout,<br />

outside-in and all-inside repair using various<br />

implants.<br />

Materials & Methods: Four cases of meniscal<br />

repair using a posterior portal to perform an allinside<br />

suture have been performed. Three<br />

involved the medial meniscus and all were<br />

associated with an ACL reconstruction. The<br />

technique will be described. Results:Three have<br />

been adequately reviewed at an average follow-up<br />

is 6 months and all are clinically healed. No MRI<br />

or second-look arthroscopies have been<br />

performed. There have been no complications<br />

attributable to the posteromedial portal or the<br />

technique. Discussion:The perceived advantages<br />

of this technique are that repairs are anatomical<br />

and performed under direct vision. There is less

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