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POSTER ABSTRACTS - ISAKOS

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Background: Arthroscopy of the knee is<br />

commonly performed as an outpatient surgical<br />

procedure and effective post-operative pain<br />

management continues to be a challenging<br />

problem. Previous studies have addressed postoperative<br />

management by examining use of intraarticular<br />

analgesia and/or modification of<br />

anesthesia techniques. No previous studies have<br />

however, evaluated the relationship between<br />

sleep deprivation and post-operative pain after<br />

knee arthroscopy. The purpose of this doubleblinded<br />

prospective placebo-controlled<br />

randomized study was to evaluate the<br />

effectiveness of a non-benzodiazepine hypnotic<br />

sleep-aid (zolpidem) in improving post-operative<br />

pain and fatigue in patients undergoing<br />

outpatient knee arthroscopy. <br />

Methods: Sixty-eight patients<br />

undergoing outpatient knee arthroscopy for<br />

treatment of meniscal tears and/or loose bodies<br />

were randomized to three treatment groups<br />

(ZOLPIDEM [24 patients], NONE [24 patients],<br />

and PLACEBO [20 patients]). All groups received<br />

post-operative hydrocodone and ibuprofen.<br />

Patients in the ZOLPIDEM group received a single<br />

dose of zolpidem for the first seven post-operative<br />

nights. Patients in the PLACEBO group received a<br />

gelatin capsule similar in appearance to zolpidem.<br />

Patients in the NONE group received only<br />

hydrocodone and ibuprofen.<br />

Results: Patients in the NONE<br />

group and PLACEBO group (no zolpidem<br />

received) demonstrated significantly worse mean<br />

daily post-operative pain scores on a visual<br />

analog scale when compared with the ZOLPIDEM<br />

group (p = 0.01 and p =0.04, respectively).<br />

Patients in the NONE group consumed<br />

significantly higher quantities of<br />

hydrocodone/acetaminophen post-operatively (p<br />

= 0.04) and had significantly more daily postoperative<br />

fatigue (p = 0.02) than the ZOLPIDEM<br />

group. Patients in the PLACEBO group also<br />

consumed higher quantities of<br />

hydrocodone/acetaminophen and had more daily<br />

postoperative fatigue although these differences<br />

did not reach statistical significance (p = 0.4 and p<br />

= 0.1, respectively). <br />

Conclusion: This study<br />

demonstrates that sleep and fatigue may be an<br />

important factor in the effective management of<br />

pain after outpatient knee arthroscopy. Future<br />

post-operative treatment regimens should<br />

address sleep and fatigue in order to maximize<br />

analgesic effects in these patients.<br />

E-poster w/ Standard #759<br />

Functional Outcome of the Arthroscopic<br />

Meniscal Transplantation Compared with the<br />

Open Meniscal Transplantation<br />

Herman Kaptijn, Leiden, NETHERLANDS,<br />

Ewoud Van Arkel, Den Haag, CK NETHERLANDS<br />

Presenter<br />

Westeinde Hospital, Den Haag,<br />

introduction:<br />

from 1998 on, 79 patients had a meniscal<br />

transplantation with a cryopreserved meniscal<br />

allograft. The first group of 63 consecutive<br />

meniscal allografts ( 57 patients) were<br />

transplanted through an open technique. The<br />

second group of 22 consecutive patients were<br />

operated through an arthroscopic assited<br />

technique. The purpose was to assess the<br />

arthroscopic technique on decreasing the<br />

rehabilitation period.<br />

Materials and methods:<br />

A retrospective cohort investigation in which the<br />

open technique of meniscal transplantation was<br />

compared to the arthroscopic assisted technique.<br />

Both groups were scored according to the<br />

Lysholm score pre-operative and at 6 months and<br />

12 months postoperative. The failures were<br />

analysed. To compare the groups a student-t test<br />

was used (p

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