POSTER ABSTRACTS - ISAKOS

chondromalacia may represent a relative
contraindication to meniscus transplantation.
E-poster #769
Granulate or Rigid Wedge Tricalcium
Phosphate Performs in Open Wedge High
Tibial Osteotomy: A Radiologic Study with a
New Evaluation System.
Ronald van Heerwaarden, Nijmegen,
NETHERLANDS, Presenter
Wouter van Hemert, Nijmegen, NETHERLANDS
Karel Willems, Nijmegen, NETHERLANDS
Patsy Anderson, Nijmegen, NETHERLANDS
Ate Binne Wymenga, Nijmegen, NETHERLANDS
Sint Maartenskliniek, Nijmegen, NETHERLANDS
The capacity of two forms of porous betatricalcium
phosphate bone substitutes (TCP) to
promote bone healing in open wedge high tibial
osteotomy (OWHTO) was studied. We reviewed
the X-rays of 27 osteotomies, with either TCPwedges
or TCP granules as filling material, to
compare the bone healing rates and bone
remodelling, at specific postoperative intervals. A
new radiologic rating system for OWHTO was
created and tested for clinical applicability. All
osteotomies healed uneventfully and complete
resorption of TCP was demonstrated at 1 year
postoperative in 85% (n=23) of the procedures. In
44% (n=10) of these 23 procedures, the osteotomy
site was no longer visible. No difference in bone
healing rate and bone remodelling was found
when comparing the use of granules to a wedge,
and no adverse effects of TCP were observed. The
good interobserver (k=0.7) and intraobserver
(k=0.6) reliability of the new radiologic rating
system enables clinical use. Good bone healing
was found in OWHTO with both wedges and
granules of TCP.
E-poster #770
Clinical Results of Patellofemoral Full
Thickness Chondral Defects Treated With
Hyalograft®-C:
Alberto W. Gobbi, Milan, ITALY, Presenter
Ramces A. Francisco, Milan, ITALY
OASI, Milan, ITALY
Aim of the study: Patellofemoral chondral lesions
represents a severe problem for the orthopaedic
surgeons. The use of tissue engineering has
emerged as a potential therapeutic option for
cartilage regeneration. The aim of our prospective
study was to evaluate the efficacy of Hyalograft®-
C, hyaluronan-based scaffold cultivated with
autologous chondrocytes, in a group of patients
with full thickness patellofemoral defects.
Method: We conducted a prospective evaluation
of 14 patients (10 male and 4 females) treated
with Hyalograft®-C at our institutions for
patellofemoral chondral lesions. Average age was
34 yrs. (min.18 max. 55) and the mean follow-up
period was 24 months (max 37). The defect area
was 8.2 cm2 and the lesions were due to trauma
in 8 patients, malalignment in 2 and sportsrelated
microtrauma in 4. Three patients had
underwent previous surgery and 1 patient had
concomitant lateral release. Subjective
evaluation, pre- and post-op pain assessment
with VAS scale, ICRS-IKDC 2000 scores were used
for final evaluation. All patients underwent MRI at
12 months. In two patients a 2nd-look
arthroscopy and biopsy was performed. Student-
T Test was used for statistical analysis.
Results: A significant improvement (p