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Conference Program of WCICA 2012

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<strong>Conference</strong> <strong>Program</strong> <strong>WCICA</strong> <strong>2012</strong><br />

Automatic Sleep Stage Classification Based on ECG and EEG Features<br />

for Day Time Short Nap Evaluation, pp.4974–4977<br />

Yu, Shanshan<br />

Chen, Xi<br />

Wang, Bei<br />

Wang, Xing-yu<br />

East China Univ. <strong>of</strong> Sci. & Tech.<br />

East China Univ. <strong>of</strong> Sci. & Tech.<br />

East China Univ. <strong>of</strong> Sci. & Tech.<br />

East China Univ. <strong>of</strong> Sci. & Tech.<br />

In this study, the Electrocardiogram (ECG) and Electroencephalogram<br />

(EEG) data recorded during day time short nap were analyzed. The ultimate<br />

purpose is to find out effective ECG features combined with usual<br />

EEG features for sleep stage determination during day time nap. Firstly,<br />

the ECG data was pre-processed in order to eliminate artifacts. After<br />

preprocessing, the second-order derivative <strong>of</strong> the ECG signal was calculated<br />

and clustered into two classes by K-means method. The peak<br />

positions <strong>of</strong> R wave were detected. Secondly, the Heart Rate Variability<br />

(HRV) was calculated according to the RR intervals (RRIs). Features<br />

<strong>of</strong> HRV <strong>of</strong> ECG were extracted in time-domain and frequency-domain.<br />

The redundant features were removed by the rough set method. Finally,<br />

the extracted features from the HRV <strong>of</strong> ECG were combined with the<br />

usual EEG features for sleep stage determination. The sleep stages including<br />

stage awake, stage 1 and stage 2 were distinguished by using<br />

Support Vector Machine (SVM). The obtained result indicated that the<br />

extracted ECG features improved the sleep stage classification accuracy.<br />

◮ SuB05-2 16:10–16:30<br />

Optimal Control in Molecular-level Gene Manipulation, pp.4978–4983<br />

Yu, Juanyi<br />

Li, Jr-Shin<br />

Washington Univ. in St. Louis<br />

Washington Univ. in St. Louis<br />

The sequential information stored in DNA determines the appearance<br />

and inheritance <strong>of</strong> different life forms and individuals. Precision control<br />

<strong>of</strong> DNA sequences at the molecular level is crucial to maintain the fidelity<br />

<strong>of</strong> genes and to ensure the accuracy <strong>of</strong> gene expression. In this<br />

paper, we propose state-space control models at the molecular level<br />

by converting character-based DNA sequences into state vectors and<br />

incorporating on/<strong>of</strong>f controls for mutagens into DNA replication systems<br />

in different scales. Subsequently, we compute the optimal control<br />

sequence for minimizing the risk <strong>of</strong> applying mutagens and the <strong>of</strong>ftrajectory<br />

penalty using dynamic programming algorithm. By the brute<br />

force method and simulation results, we conclude that the global optimum<br />

can always be achieved within a finite number <strong>of</strong> steps <strong>of</strong> deterministic<br />

DNA replication systems. The upper limit <strong>of</strong> steps to reach the<br />

global optimum depends on the length <strong>of</strong> the DNA sequence.<br />

◮ SuB05-3 16:30–16:50<br />

Multivariate Statistical Analysis Methods to Investigate Interindividual<br />

Glucose Dynamics for Subjects with Type 1 Diabetes Mellitus, pp.4989–<br />

4994<br />

Zhao, Chunhui<br />

Sun, Youxian<br />

Gao, Furong<br />

Zhejiang Univ.<br />

Zhejiang Univ.<br />

Hong Kong Univ. <strong>of</strong> Sci. & Tech.<br />

This paper investigates the interindividual variability <strong>of</strong> underlying glucose<br />

dynamics using multivariate statistical analysis methods for subjects<br />

with type 1 diabetes mellitus. Here two types <strong>of</strong> glucose dynamics<br />

are defined, the general dynamics and the output-relevant predictive<br />

dynamics. The concerned important issues are whether the underlying<br />

glucose dynamics change from subject to subject? Can a global<br />

(or universal) empirical model be developed from glucose data for a s-<br />

ingle subject and then used to explain the glucose dynamics for other<br />

subjects? These and related issues are investigated using multivariate<br />

statistical analysis methods based on clinical data for two groups<br />

<strong>of</strong> subjects. Together, these findings provide insights into more efficient<br />

development <strong>of</strong> data-driven models to understand and capture the glucose<br />

information in diabetes subjects.<br />

◮ SuB05-4 16:50–17:10<br />

Dynamic Feature Extraction <strong>of</strong> Epileptic EEG Using Recurrence Quantification<br />

Analysis, pp.5019–5022<br />

Chen, Lanlan<br />

East China Univ. <strong>of</strong> Sci. & Tech.<br />

Zhang, Jian<br />

Zou, Junzhong<br />

East China Univ. <strong>of</strong> Sci. & Tech.<br />

East China Univ. <strong>of</strong> Sci. & Tech.<br />

Detecting the reliable transition point embedded in the electroencephalograms<br />

(EEGs) is a challenge in the field <strong>of</strong> epileptic research.<br />

In this research, a recurrence quantification analysis (RQA) is proposed<br />

to help medical doctors to reveal dynamical characteristics in EEGs <strong>of</strong><br />

patients suffering from epilepsy. In contrast with traditional chaos methods,<br />

the merits <strong>of</strong> RQA method is that it can measure the complexity<br />

<strong>of</strong> a short and non-stationary signal without any assumptions such as<br />

linear, stationary and noiseless noise. In this study, EEGs with generalized<br />

epilepsy were collected in Epilepsy Center <strong>of</strong> Renji Hospital. The<br />

test results show that three RQA measurements, i.e. recurrence rate,<br />

determinism and entropy can track the complexity changes <strong>of</strong> brain<br />

electrical activity. RQA variables show a large fluctuation in pre-ictal<br />

stage, which reflects a transitional state leading to seizure activity. On<br />

the contrary, RQA variables fluctuate in relatively small bounds in ictal<br />

stage, which is due to organized and self-sustained rhythmic discharge.<br />

Therefore, RQA could be a promising approach in prediction and diagnosis<br />

for epileptic seizures.<br />

◮ SuB05-5 17:10–17:30<br />

Key-frame Selection in WCE Video Based on Shot Detection, pp.5030–<br />

5034<br />

Fu, Yanan<br />

Liu, Haiying<br />

Cheng, Yu<br />

Yan, Tingfang<br />

Li, Teng<br />

Meng, Max, Q.-H.<br />

shandong Univ.<br />

Shandong Unversity<br />

Shandong Univ.<br />

Shandong Univ.<br />

Shandong Univ.<br />

The Chinese Univ. <strong>of</strong> Hong Kong<br />

Wireless Capsule Endoscopy (WCE) is an imaging technology that enables<br />

close examination <strong>of</strong> the interior <strong>of</strong> the entire small intestine. A<br />

major problem associated with this new technology is that a large number<br />

<strong>of</strong> images need to be manually examined by clinicians. It is therefore<br />

useful to automatically reduce the number <strong>of</strong> frames that need direct<br />

interpretation by a clinician. In this paper a technique based on<br />

shot detection method is presented for automatic key-frame selection<br />

in WCE videos. The frames in the small intestine zone containing relevant<br />

features are extracted from the video sequence as the key-frames.<br />

Experimental results show that the proposed key-frame selection techniques<br />

signi&#64257;cantly reduce the number <strong>of</strong> frames that need to<br />

be directly viewed by clinicians, and speed up the diagnosis procedures.<br />

◮ SuB05-6 17:30–17:50<br />

Patient Data Tracking in a Collaborative Healthcare, pp.5045–5050<br />

Memon, Qurban<br />

Khoja, Shakeel<br />

UAE Univ.<br />

IBA, Pakistan<br />

It has been found that patients do suffer from queuing at reception,<br />

pharmacy, appointments, and services departments <strong>of</strong> the hospitals.<br />

In this paper, patient tracking is presented such that it enables not only<br />

presence <strong>of</strong> the patient within each service area <strong>of</strong> the hospital but<br />

helps in retrieving relevant medical records <strong>of</strong> the patient from another<br />

hospital within a collaborative health care domain. The architectural<br />

challenges are investigated, and a framework for such a collaborative<br />

region is presented. The patient record database is developed, technologies<br />

are chosen and role based access for purpose <strong>of</strong> privacy is<br />

exemplified for a typical environment. The issues related to its deployment<br />

are also discussed.<br />

SuB06 16:10–17:50 Room 302<br />

Invited Session: Robot Sensing and Control<br />

Chair: Liu, Yun-Hui<br />

The Chinese Univ. <strong>of</strong> Hong Kong<br />

◮ SuB06-1 16:10–16:30<br />

Design <strong>of</strong> an Optimal Flight Control System with Integral Augmented<br />

Compensator for a Nonlinear UAV Helicopter, pp.3927–3932<br />

Tang, Yirui<br />

Li, Yangmin<br />

Univ. <strong>of</strong> Macau<br />

Univ. <strong>of</strong> Macau<br />

This paper presents the development <strong>of</strong> an optimal flight control system<br />

218

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