第10期 - 中华行为医学与脑科学杂志

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中 华 行 为 医 学 与 脑 科 学 杂 志 2012 年 10 月 第 21 卷 第 10 期 ChinJBehavMed&BrainSci,October2012,Vol.21,No.10
参 考 文 献
[1] RothwelNJ,HopkinsSJ.CytokinesandthenervoussystemⅡ:Actions
andmechanismsofaction.TrendsNeurosci,1995,18:130136.
[2] RothwelNJ,ReltonJK.Involvementofinterleukin1andlipocortin1
inischaemicbraindamage.CerebrovascBrainMetabRev,1993,5:
178198.
[3] RothwelN.Interleukin1andneuronalinjury:mechanisms,modifica
tion,andtherapeuticpotential.BrainBehavImmun,2003,17:152
157.
[4] RothwelN,AlanS,ToulmondS.Theroleofinterleukin1inacute
neurodegenerationandstroke:pathophysiologicalandtherapeuticim
plications.JClinInvest,1997,100:26482652.
[5] MachadoVieiraR,SalvadoreG,DiazgranadosN,eta1.Ketamineand
thenextgenerationofantidepresantswitharapidonsetofaction.
PharmacolTher,2009,123:143150.
[6] LanaiF,MenahemS.Miniaturesynapticcurentsbecomeneurotoxicto
chronicalysilencedneurons.CerebCortex,2007,17:12921306.
[7] ChenBS,RocheKW.RegulationofNMDAreceptorsbyphosphoryla
tion.Neuropharmacology,2007,53:362368.
[8] KuriyamaI,AsanoN,KatoI,eta1.Dipeptidealcoholbasedinhibitors
ofeukaryoticDNA polymerasealpha.BioorgMedChem,2005,l3:
21872196.
[9] SamaMA,MathisDM,FurmanJL,etal.Interleukin1betadependent
signalingbetweenastrocytesandneuronsdependscriticalyonastro
cyticcalcineurin/NFAT activity.JBiolChem,2008,283:21953
21964.
[10]PetrovaLN,Grigor'evVV,BachurinSO.Efectofinterleukin1betaon
NMDAinduced 45 Ca 2+ uptakebysynaptosomesofratbraincortex.
BulExpBiolMed,2005,140:693694.
[11] BaamondeA,HidalgoA,MenéndezL.InvolvementofglutamateNM
DAandAMPAreceptors,glialcelsandIL1βinthespinalhyperalge
siaevokedbythechemokineCCL2inmice.NeurosciLet,2011,502:
178181.
[12] ShimizuK,ChaiB,LagraizeSC,etal.MicroinjectionofIL1βintothe
trigeminaltransitionzoneproducesbilateralNMDAreceptordepend
entorofacialhyperalgesiainvolvingdescendingcircuitry.OpenPainJ,
2009,2:7683.
[13]GardoniF,BorasoM,ZianniE,etal.Distributionofinterleukin1re
ceptorcomplexatthesynapticmembranedrivenbyinterleukin1βand
NMDAstimulation.JNeuroinflammation,2011,8:14.
[14] BrustovetskyT,BritainMK,SheetsPL,etal.KBR7943,aninhibitor
ofthereverseNa + /Ca 2+ exchanger,blocksNmethylDaspartatere
ceptorandinhibitsmitochondrialcomplexI.BrJPharmacol,2011,
162:255270.
[15] TsakiriN,KimberI,RothwelNJ,etal.Interleukin1inducedinter
leukin6synthesisismediatedbytheneutralsphingomyelinase/Srcki
nasepathwayinneurones.BrJPharmacol,2008,153:77583.
[16] HuangY,SmithDE,IbáezSandovalO,etal.Neuronspecificefects
ofinterleukin1βaremediatedbyanovelisoformoftheIL1receptor
accesoryprotein.JNeurosci,2011,31:1804818059.
[17] ZhangRX,LiA,LiuB,WangL,eta1.IL1raaleviatesinflammatory
hyperalgesiathroughpreventingphosphorylationofNMDA receptor
NR1subunitinrats.Pain,2008,135:232239.
[18] UlteniusC,LinderothB,MeyersonBA,etal.SpinalNMDAreceptor
phosphorylationcorelateswiththepresenceofneuropathicsignsfol
lowingperipheralnerveinjuryintherat.NeurosciLet,2006,399:85
90.
[19] WeiF,GuoW,ZouS,etal.Supraspinalglialneuronalinteractions
contributetodescendingpainfacilitation.JNeurosci,2008,28:10482
10495.
[20] 刘 国 军 , 黄 建 敏 , 李 雪 斌 , 等 . 吡 咯 烷 二 硫 代 氨 基 甲 酸 盐 对 癫 痫 大
鼠 海 马 NFκB 及 相 关 炎 症 因 子 表 达 的 影 响 . 中 华 行 为 医 学 与 脑
科 学 杂 志 ,2011,20:784786.
[21] 王 争 艳 , 周 厚 纶 , 刘 庆 莹 , 等 .IL1β 对 谷 氨 酸 致 痫 大 鼠 大 脑 皮 质 、
海 马 内 NMDAR 免 疫 反 应 变 化 的 影 响 . 神 经 解 剖 学 杂 志 ,2004,
20:5559.
[22]GuoW,WangH,WatanabeM,etal.Glialcytokineneuronalinterac
tionsunderlyingthemechanismsofpersistentpain.JNeurosci,2007,
27:60066018.
[23]ZhengH,ZhuW,ZhaoH,etal.Kainicacidactivatedmicrogliamedi
ateincreaseexcitabilityofrathippocampalneuronsinvitroandinvi
vo:crucialroleofinterleukin1beta.Neuroimmunomodulation,2010,
17:3138.
[24]GaoYJ,JiRR.TargetingAstrocyteSignalingforChronicPain.Neuro
therapeutics,2010,7:482493.
[25] VivianiB,GardoniF,BartesaghiS,etal.Interleukin1betareleased
bygp120drivesneuraldeaththroughtyrosinephosphorylationand
trafickingofNMDAreceptors.JBiolChem,2006,281:3021230222.
[26]JingT,WuL,BorgmannK,etal.SolublefactorsfromIL1βstimula
tedastrocytesactivateNR1a/NR2Breceptors:implicationsforHIV1
inducedneurodegeneration.Biochem BiophysResCommun,2010,
402:241246.
[27]LundborgC,WesterlundA,BjrklundU,etal.IfenprodilrestoresGD
NFevokedCa 2+ signalingandNa + /K + ATPaseexpresioninin
flammationpretreatedastrocytes.JNeurochem,2011,119:686696.
[28]BalosoS,MarosoM,SanchezAlavezM,etal.Anovelnontranscrip
tionalpathwaymediatestheproconvulsiveefectsofinterleukin1beta.
Brain,2008,131:32563265.
[29]OrikawaY,KatoH,SetoK,KobayashiN,etal.Z360,anovelthera
peuticagentforpancreaticcancer,preventsupregulationofephrinB1
geneexpresionandphosphorylationofNR2Bviasuppresionofinter
leukin1βproductioninacancerinducedpainmodelinmice.Mol
Pain,2010,6:72.
[30]GalicMA,RiaziK,HendersonAK,etal.Virallikebraininflammation
duringdevelopmentcausesincreasedseizuresusceptibilityinadult
rats.NeurobiolDis,2009,36:343351.
[31]LiuS,XuGY,JohnsonKM,etal.Regulationofinterleukin1betaby
theinterleukin1receptorantagonistintheglutamateinjuredspinal
cord:endogenousneuroprotection.BrainRes,2008,1231:6374.
[32]LiuCH,CherngCH,LinSL,etal.NmethylDaspartatereceptoran
tagonistMK801suppresesglialproinflammatorycytokineexpresion
inmorphinetolerantrats.PharmacolBiochem Behav,2011,99:371
380.
[33]WangW,MeiXP,WeiYY,etal.NeuronalNR2BcontainingNMDA
receptormediatesspinalastrocyticcJunNterminalkinaseactivation
inaratmodelofneuropathicpain.BrainBehavImmun,2011,25:
13551366.
[34]AlAminH,SarkisR,AtwehS,etal.Chronicdizocilpineorapomor
phineanddevelopmentofneuropathyintwoanimalmodelsI:efects
onbraincytokinesandneurotrophins.ExpNeurol,2011,228:3040.
[35] WangP,RothwelNJ,PinteauxE,etal.Neuronalinjuryinducesthe
releaseofprointerleukin1betafromactivatedmicrogliainvitro.Brain
Res,2008,236:17.
( 收 稿 日 期 :2012-05-04)
( 本 文 编 辑 : 冯 学 泉 )