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Descriptive Psychopathology: The Signs and Symptoms of ...

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129 Appendix 5.1: Questions for past illness10 One <strong>of</strong> us (MAT) was the principle investigator on a large project that gathered informationfrom first-degree relatives <strong>of</strong> patients with either schizophrenia or a mood disorder.Whenever possible, relatives were personally interviewed, but they also provided informationabout the patient <strong>and</strong> other relatives. Mothers gave the most <strong>and</strong> the most reliableinformation. Older sisters were the next best source. <strong>The</strong> information from patients’ fatherswas highly variable in quality <strong>and</strong> quantity.11 Obtaining the ages <strong>and</strong> names <strong>of</strong> close family members accomplishes two things. First, itprovides some assessment <strong>of</strong> the patient’s biographic memory <strong>and</strong> cognitive difficulties.Second, the ages <strong>of</strong> the family members can be compared to the age <strong>of</strong> risk for diseasesin the differential diagnosis, <strong>and</strong> whether they are in the risk period. For example, ifHuntington’s disease is a consideration, but the health <strong>of</strong> the patient’s parents is unknown<strong>and</strong> the patient’s siblings appear healthy, healthy siblings over age 60 are unlikely to have theillness, but healthy siblings under age 30 are yet to enter the peak risk period.12 Levin et al. (1985).13 Peleg <strong>and</strong> Shalev (2006).14 Covey et al. (1998).15 Kaufman <strong>and</strong> Sachdeo (2003); Bonilha <strong>and</strong> Li (2004).16 CAGE is a four-item screening acronym assessing for alcoholism <strong>and</strong> st<strong>and</strong>ing for cuttingdown, annoyed by criticism, guilt feelings, <strong>and</strong> having eye-openers.17 Fink et al. (2002).18 Chung <strong>and</strong> Martin (2005).19 Enevoldson (2004); Winger et al. (2005).

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