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Descriptive Psychopathology: The Signs and Symptoms of ...

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313 Chapter 13: Testing <strong>and</strong> psychopathology <strong>of</strong> cognitive dysfunction<strong>The</strong> consultant suggested the group move to a larger room <strong>and</strong> asked thepatient if he knew the room with “the piano” <strong>and</strong> could he lead the group to it.<strong>The</strong> inpatient unit was shaped like an H, with the patient’s room at the bottom<strong>of</strong> the lower left section <strong>and</strong> the piano room in the top <strong>of</strong> the upper rightsection. With a perfectly normal, smooth gait the patient led the team out <strong>of</strong>his room. He immediately turned to his left, walked to the transept, turnedright, crossed to the other hallway, turned left <strong>and</strong> walked to the piano roomwhere he pointed to the piano. As the team was getting settled to observe theconsultant’s “bedside” cognitive testing, he turned to the patient’s geriatricpsychiatrist <strong>and</strong> whispered, “Well, I’ve just completed most <strong>of</strong> my evaluation.<strong>The</strong> patient does not have Alzheimer’s disease.” Further assessment wasconsistent with the clinical interpretation <strong>and</strong> indicated the patient hadmodest impairment on tasks associated with frontal lobe disease. Functionalimaging confirmed mild primary frontal lobe atrophy without evidence <strong>of</strong>vascular disease.Patient 13.2 had been in slow decline for six years. Although there is an earlyonsetform <strong>of</strong> Alzheimer’s disease it is virulent, associated with a strong familyhistory for the illness, <strong>and</strong> about 30% <strong>of</strong> sufferers will have associated increasedmuscle tone or rigidity. Alzheimer’s disease typically begins with problems invisual–spatial functioning <strong>and</strong> new learning. Patient 13.2’s facial recognition <strong>of</strong>his physicians, learning the unit’s floor plan <strong>and</strong> being able to easily negotiate itsconfiguration, remembering where the piano was, <strong>and</strong> being able to lead the teamto the correct room with a smooth gait, eliminated Alzheimer’s disease fromserious consideration. 12 Accomplishing all that while still maintaining socialgraces further indicated that Patient 13.2’s cognitive decline associated with hisapathetic syndrome was likely to be modest. Functional imaging, other history<strong>and</strong> examination findings also demonstrated that the apathy was not due tovascular disease or depressive illness.Many behaviors signal specific cognitive difficulties <strong>and</strong> their presence shapethe choice <strong>of</strong> st<strong>and</strong>ardized tasks. Table 13.1 displays the more common <strong>of</strong>signature behaviors. Along with the assessment for patterns <strong>of</strong> abnormal motorfeatures, bedside cognitive testing helps identify the circumscribed brain lesionsthat may underlie the behavioral syndrome.Principles <strong>of</strong> bedside cognitive assessmentReasons for assessmentTable 13.2 displays reasons for cognitive assessment. Relying on screening batteriessuch as <strong>The</strong> Mini Mental State Examination (MMSE) is <strong>of</strong> modest utility only

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