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Descriptive Psychopathology: The Signs and Symptoms of ...

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32 Section 1: Present, past, <strong>and</strong> futurethat were considered deranged in mental illness. Although his scheme wasillogical as he included the same syndrome in several etiologic categories,his linking <strong>of</strong> insanity to specific mental domains foreshadowed Kraepelin’sreliance on will, thought, <strong>and</strong> emotion in distinguishing dementia praecox <strong>and</strong>manic-depressive insanity. 67<strong>The</strong> nineteenth-century French psychiatrist Benedict Augustin Morel introducedthe term dementia praecox. His characterization <strong>of</strong> the condition wasincorporated by Kraepelin into the disease model that would become schizophrenia.Morel also classified psychiatric disturbances by the presence or absence <strong>of</strong>perceived hereditary factors. 68Daniel Hack Tuke, from a distinguished family committed to the care <strong>of</strong>the mentally ill, <strong>of</strong>fered a classification that influenced late-nineteenth-centuryBritish thinking. Tuke’s collaboration with Charles Bucknill resulted in the 1858publication <strong>of</strong> the Manual <strong>of</strong> Psychological Medicine that became a st<strong>and</strong>ardtextbook <strong>of</strong> psychiatry for the rest <strong>of</strong> the century. Tuke introduced the term“psycho-therapeutics” in 1872. He followed with the Dictionary <strong>of</strong> PsychologicalMedicine in 1892, a work <strong>of</strong> 128 contributors. In 1880 he became the editor <strong>of</strong> theJournal <strong>of</strong> Mental Science, the fore-runner <strong>of</strong> the British Journal <strong>of</strong> Psychiatry. 69Neurology <strong>and</strong> psychiatry had not yet fully separated, <strong>and</strong> in the latter half <strong>of</strong>the nineteenth century efforts were made to find the specific brain areas involvedin the different behavioral disorders. This effort was an extension <strong>of</strong> Griesinger’slabors to make the field more scientific <strong>and</strong> the earlier work <strong>of</strong> Willis (whoconsidered different functions for white <strong>and</strong> gray matter), Dax (who associateda loss <strong>of</strong> thinking abilities to left hemisphere cortical injury), Broca (who characterizedmotor aphasia) <strong>and</strong> Meynart (who observed that motor functions werelargely subserved by frontal brain regions). 70Carl Wernicke, pr<strong>of</strong>essor <strong>of</strong> psychiatry <strong>and</strong> neurology at the University <strong>of</strong>Breslau, <strong>of</strong>fered an extensive formulation <strong>of</strong> the relationship between brainstructure <strong>and</strong> behavioral disturbance (Grundrib der Psychiatrie or Basic Psychiatry)that evolved from his study <strong>of</strong> aphasia. Wernicke forced his classificationinto his ideas <strong>of</strong> brain localization rather than basing it on more objective study. 71Karl Jaspers called him a “brain mythologist” <strong>and</strong> compared Wernicke to Freud,writing that both made generalizations beyond the facts <strong>and</strong> produced onlyabstract constructions. 72<strong>The</strong> quest for localizing psychiatric disease to specific brain regions wascontinued by Bonhoeffer (acute reactive psychosis), Liepman (secondary psychosis)<strong>and</strong> Karl Kleist. 73 Kleist had the most success in seeing the associationbetween psychomotor disturbances (e.g. catatonia, melancholia) <strong>and</strong> basalganglia <strong>and</strong> other frontal brain region disease. 74 He also coined the term “cycloidpsychosis” later elaborated by Karl Leonhard.

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