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Descriptive Psychopathology: The Signs and Symptoms of ...

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154 Section 3: Examination domainsTable 7.1. Diseases commonly associated with motor <strong>and</strong> mood disorderParkinson’s diseaseHuntington’s diseaseWilson’s diseaseAlzheimer’s diseaseEpilepsyMigraineTraumatic brain injurySchizophreniaAutistic spectrum disorderEncephalitisDemyelinating diseaseStrokeAutoimmune diseaseToxic encephalopathyEndocrinopathiesMelancholiaManiapathogenesis <strong>of</strong> autistic spectrum disorders <strong>and</strong> schizophrenia. 10 Both conditionsare characterized by abnormal emotional expression, including the movements <strong>of</strong>emotions (e.g. facial expression, h<strong>and</strong> gestures), <strong>and</strong> in the recognition <strong>of</strong> theemotional valence expressed by others. 11 <strong>The</strong> examinations <strong>of</strong> motor <strong>and</strong> emotionsystems are conjoined. Underst<strong>and</strong>ing their related psychopathology isessential to diagnosing behavioral syndromes.Disturbances in activityAbnormal activity level is common among patients with behavioral illness.Determining what the patient does during a typical day or observing the patientin the waiting area, examining room, or in the common areas <strong>of</strong> the inpatientunit reveals many <strong>of</strong> these disturbances.HyperactivityHyperactive patients exhibit many actions simultaneously or in a short period <strong>of</strong>time. <strong>The</strong>y rush from one undertaking to the next. Severe hyperactivity appears asfrenzy, the patient failing to complete even simple household or personal hygienetasks. <strong>The</strong> lack <strong>of</strong> an apparent goal in the plethora <strong>of</strong> activity, however, does notdelineate syndromes. It is a sign <strong>of</strong> severity, not <strong>of</strong> specific pathophysiology.Hyperactivity is the motor equivalent <strong>of</strong> distractibility <strong>and</strong> flight-<strong>of</strong>-ideas(thought associations that jump from topic to topic). It is a classic feature <strong>of</strong>mania <strong>and</strong> stimulant drug intoxication.When severe, hyperactivity is associated with excitement (extreme hyperarousal<strong>and</strong> intense emotional expression), a state termed manic delirium.Almost all such patients will have catatonic features. 12 A hyperkinetic state is alsoseen in children with complex partial seizures. This state can be intense, involvingfrenetic movements <strong>of</strong> the extremities <strong>and</strong> trunk. Flailing, kicking, screaming,

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