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Download (3100Kb) - Etheses - Saurashtra University

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[F] Antimicrobial activity of 6-(2-(4-chlorophenyl)-8-methyl-1H-imidazo[1,2-a]pyridine-3-yl)-4-aryl pyrimidine-2(H)-thione.Antimicrobial testing was carried out as described in part- I ExperimentalSection [E] Page No. 38. The zone of inhibition of the test solution are recorded inTable No.- 2(IIA).TABLE NO.- 2(IIA) BIOLOGICAL SCREENING OF 6-(2-(4-CHLOROPHENYL)-8-METHYL-1H-IMIDAZO[1,2-a]PYRIDINE-3-YL)-4-ARYL PYRIMIDINE-2(H)-THIONE.Zone of inhibition in m.mSr.RAntibacterialAntifungalNo.B.coccus S.aureus Pseudo E.coli A.nigermona2(IIa) C 6 H 5 - 16 15 16 18 162(IIb) 4-CH 3 -C 6 H 4 - 15 14 12 13 142(IIc) 4-OCH 3 -C 6 H 4 - 14 13 15 12 132(IId) 4-Cl-C 6 H 4 - 16 17 14 16 182(IIe) 4-F-C 6 H 4 - 15 16 12 14 142(IIf) 4-Br-C 6 H 4 - 13 12 13 14 152(IIg) 4-NH 2 -C 6 H 4 - 15 13 14 12 162(IIh) 4-NO 2 -C 6 H 4 - 12 14 12 14 152(IIi) 4-OH-C 6 H 4 - 17 16 18 17 16Std n Ampicillin 20 21 22 21 -” Amoxicillin 22 23 21 20 -” Ciprofloxacin 23 22 24 22 -” Norfloxacin 21 24 22 23 -” Greseofulvin - - - - 2587Thiopyrimidine…..

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