Download (3100Kb) - Etheses - Saurashtra University

Moreover, Nomura Yutaka et al. 487 synthesized epoxy succinic acidderivatives which are useful in the prevention of treatement of bone diseases suchas osteoporosis, Malignant hyperalemia and in the treatment of osteoarthritis andrheumatold arthritis. Kikkawa Kosi 488 and co-workers synthesised epoxidederivatives (V) which exhibited 100% herbicidal activity against panciu, crusgalli andscirpus juncoides respectively with no damage on rice.OC H 3OR 1H 3 CS NR 1NR 2( V ) ( VI )Moder Kennteth Philip 489 have reported epoxides ( VI ) as antiulcer agents.Some oxirane carboxylic acid and esters are useful as intermediate forhypoglycemics and hypolipeacics Rose Henry J. 490 synthesised epoxide derivativeshaving potent fungicidal activity. Some epoxides have been reported as insecticidesand pesticides. Hamaguchi Shigeki et. al. 491 synthesized some optically active halomethyl oxirane useful as insect pheromones. Neef Gunter and co-worker 492prepared Gonene epoxide and reported that it can be used as intermediates forantigestanenes and antiglucocorticoides. Oesch F. et al. 493 reported enzymeinhibitor activity of oxirane. Tsunemoto Daiei et. al. and Kawamura Yasuo et al. 494synthesized oxirane derivatives (VII) which are useful as herbicides.150Oxirane…..