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RNNHHNNNH 2NH 2a- R :H; pera connectionb- R :H; meta connectionType-VIJames J. Kaminski and co-workers 46 had been synthesized somenovel compounds such as 3-(cyanomethyl)-2-methyl-8-(2-phenylethyl) imidazo[1,2-a]pyridine (Type-VII) and 2,3-dimethyl-8-(phenylmethoxy)imidazo[1,2-a]pyridine(Type-VIII). Which shows Gastric-Antisecretory and Cytoprotective Properties.ONNCH 2 CNCH 3NNCH 3CH 3Type-VIIType-VIII20Introduction of Chalcone…..
S. Kristjan, Gudmundsson and A. Brain Johns 47 and A.Chaouni-Bendallahet al. 48 worked on synthesis of a novel imidazo[1,2-a]pyridine shown in Type-IX withpotent activity against herpes simpex viruses.HNFNNNNNHType-IXThus the important role displayed by imidazo[1,2-a]pyridine and it’sderivatives for various therapeutic and biological activities promoted us tosynthesise some chalcone and acetylpyrazoline derivatives bearing imidazo[1,2-a]pyridine moiety in order to achive compounds having better activities.21Introduction of Chalcone…..
Page 3: The Sarvodaya Education Society’s
Page 6 and 7: selfless help, moral support and gu
Page 9 and 10: Introduction and Spectral studies .
Page 11 and 12: “STUDIES ON SOME HETEROCYCLICENTI
Page 13 and 14: Pyrimidine derivatives have been pr
Page 15 and 16: Isoxazole derivative synthesized by
Page 17 and 18: “STUDIES ON SOMEHETEROCYCLIC ENTI
Page 19 and 20: (b) Pharmacokinetics: It is derived
Page 21 and 22: (C) Drug DevelopmentMany natural pr
Page 23 and 24: The process of drug design is exten
Page 25 and 26: (l) Non steroidal anti-inflammatory
Page 27 and 28: INTRODUCTIONThe aza-indolizine cont
Page 29 and 30: PHARMACEUTICAL IMPORTANTMuch resear
Page 31: Compd. R 1 R 2 R 3a :- H 7-Me-6,8-B
Page 35 and 36: STUDIES ON IMIDAZOPYRIDINE DERIVATI
Page 37 and 38: (a) Chalcones with monoethanolamine
Page 39 and 40: Das B.P. et al. 111 have found that
Page 41 and 42: Furthermore, Alcaraz M.J, et al. 13
Page 43 and 44: REACTION SCHEMECl+ClOClOClClCH 3NH
Page 45 and 46: Instrument : SHIMADZU FTIR 8400 Spe
Page 47 and 48: SignalNo.SignalPosition(δppm)Relat
Page 49 and 50: ANTIMICROBIAL ACTIVITYProducts : Ch
Page 51 and 52: The reaction mixture was poured on
Page 53 and 54: TABLE NO.- 1A BIOLOGICAL SCREENING
Page 55 and 56: PART-IISTUDIES ON PYRIMIDINES
Page 57 and 58: The self consistent (pi)electron de
Page 59 and 60: class of dye viz. trichloro pyrimid
Page 61 and 62: ability to cleave nucleic acid targ
Page 63 and 64: SSNHNHoONOoONOo(11) (12)oOHThe Pyri
Page 65 and 66: called ABPP or bropirimine(2-amino-
Page 67 and 68: acid so that it could be utilized f
Page 69 and 70: have reported the 5-substitutedfuro
Page 71 and 72: maturation of the viral mRNA molecu
Page 73 and 74: Nevertheless, these compounds const
Page 75 and 76: OHHNCH 3Cl(CH 2 )nSNNR 2R 1N H 2NSR
Page 77 and 78: SECTION-ISTUDIES ONOXOPYRIMIDINES
Page 79 and 80: PHARMACEUTICAL IMPORTANCEIn recent
Page 81 and 82: REACTION SCHEMECH 3NNCHOCl10% KOH R
Page 83 and 84:
INSTRUMENT :SHIMADZU FTIR 8400 Spec
Page 85 and 86:
SignalNo.SignalPosition(δppm)Relat
Page 87 and 88:
EXPERIMENTALSynthesis and therapeut
Page 89 and 90:
TABLE NO.- 2(IB)PHYSICAL CONSTANTS
Page 91 and 92:
INTRODUCTIONThiopyrimidine derivati
Page 93 and 94:
H 3 COHNRH 3 CH 3 CNHS( IV ) R = ar
Page 95 and 96:
SYNTHESIS AND THERAPEUTIC EVALUATIO
Page 97 and 98:
IR SPECTRAL STUDIES OF 6-(2-(4-CHLO
Page 99 and 100:
NMR SPECTRAL STUDIES OF 6-(2-(4-CHL
Page 101 and 102:
MASS SPECTRAL STUDIES OF 6-(2-(4-CH
Page 103 and 104:
[F] Antimicrobial activity of 6-(2-
Page 105 and 106:
SECTION-IIISTUDIES ONAMINOPYRIMIDIN
Page 107 and 108:
ArCHO+ArCOCH3NaOHMethanolR R 1ONaOH
Page 109 and 110:
Page 111 and 112:
IR SPECTRAL STUDIES OF 4-(2-(4-CHLO
Page 113 and 114:
NMR SPECTRAL STUDIES OF 4-(2-(4-CHL
Page 115 and 116:
MASS SPECTRAL STUDIES OF 4-(2-(4-CH
Page 117 and 118:
[F] Antimicrobial activity of 4-(2-
Page 119 and 120:
PART-IIISTUDIES ONCYCLOHEXENONES
Page 121 and 122:
2. Michael addition of chalcone wit
Page 123 and 124:
Rheinheimer J. et al. 381have synth
Page 125 and 126:
Page 127 and 128:
IR SPECTRAL STUDIES OF ETHYL-6-(2-(
Page 129 and 130:
NMR SPECTRAL STUDIES OF ETHYL-6-(2-
Page 131 and 132:
MASS SPECTRAL STUDIES OF ETHYL-6-(2
Page 133 and 134:
Antimicrobial testing was carried o
Page 135 and 136:
PART-IVSTUDIES ON PYRAZOLINES
Page 137 and 138:
H 2 C= CHCN + Ar - NHNH 2NArN(3) 2
Page 139 and 140:
PHARMACEUTICAL IMPORTANCE :2- Pyraz
Page 141 and 142:
Kadu et al. 424 and antimicrobial b
Page 143 and 144:
REACTION SCHEMECH 3NNClCHO10% KOHRO
Page 145 and 146:
Instrument : SHIMADZU FTIR 8400 Spe
Page 147 and 148:
SignalNo.SignalPosition(δppm)Relat
Page 149 and 150:
EXPERIMENTALSynthesis and therapeut
Page 151 and 152:
TABLE NO.- 4(B)PHYSICAL CONSTANTS O
Page 153 and 154:
INTRODUCTION:Isoxazole come under t
Page 155 and 156:
PHARMACEUTICAL IMPORTANCE :Isoxazol
Page 157 and 158:
SYNTHESISAND THERAPEUTIC EVALUATION
Page 159 and 160:
IR SPECTRAL STUDIES OF 2-(4-CHLOROP
Page 161 and 162:
NMR SPECTRAL STUDIES OF 2-(4-CHLORO
Page 163 and 164:
MASS SPECTRAL STUDIES OF 2-(4-CHLOR
Page 165 and 166:
[F]Antimicrobial activity of 2-(4-c
Page 167 and 168:
PART-VISTUDIES ON OXIRANES
Page 169 and 170:
( iii ) Epoxidation can also been c
Page 171 and 172:
Moreover, Nomura Yutaka et al. 487
Page 173 and 174:
Page 175 and 176:
IR SPECTRAL STUDIES OF (3-(2-(4-CHL
Page 177 and 178:
NMR SPECTRAL STUDIES OF (3-(2-(4-CH
Page 179 and 180:
MASS SPECTRAL STUDIES OF (3-(2-(4-C
Page 181 and 182:
[F] Antimicrobial activity of (3-(2
Page 184 and 185:
1. J. A. Joule and K. Mills; Hetero
Page 186 and 187:
37. James J. Kaminski, D. G. perkin
Page 188 and 189:
78. Ms. B. S. Hastak and B. J. Ghiy
Page 190 and 191:
116. V. R. Mudalir and V. Joshi ; I
Page 192 and 193:
150. S. Inoue, A. J. Saggimoto and
Page 194 and 195:
197. S. S. Bahekar, D. B. Shinde; A
Page 196 and 197:
238. A. Kreutzberger and M. Sellhei
Page 198 and 199:
280. See, for example, W. H. Prusof
Page 200 and 201:
326. C. W. Whitehead and J. J. Trav
Page 202 and 203:
366. Nagarjan K., Shenoy S. J.; Ind
Page 204 and 205:
396. Ausra Voskiene,Vytautas Mickev
Page 206 and 207:
432. Solankee Sejal; Prajapati Yoge
Page 208 and 209:
463. Mishra Ashutosh ; Jain Sanmati
Page 210 and 211:
496. Kaneko Mashami, Saitoh Yutaka,
Page 212 and 213:
CH 3CH 3NNClNNClORHNONRRRC 6 H 5 -
Page 214 and 215:
CH 3CH 3NNClNNClEtOOCORHNNRRRC 6 H
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