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Download (3100Kb) - Etheses - Saurashtra University

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[F] Antimicrobial activity of (3-(2-(4-Chlorophenyl)-8-methyl-1H-imidazo[1,2-a]pyridine-3-yl)oxirane-2-yl) aryl methanone.Antimicrobial testing was carried out as described in part- I ExperimentalSection [E] Page No. 38. The zone of inhibition of the test solution are recorded inTable No.- 6(A).TABLE NO.- 6(A)BIOLOGICAL SCREENING OF (3-(2-(4-CHLOROPHENYL)-8-METHYL-1H-IMIDAZO[1,2-a]PYRIDINE-3-YL)OXIRANE-2-YL) ARYL METHAN-ONE.Zone of inhibition in m.mSr.RAntibacterialAntifungalNo.B.coccus S.aureusPseudoE.coli A.nigermona6a C 6 H 5 - 17 16 15 18 166b 4-CH 3 -C 6 H 4 - 14 14 12 13 146c 4-OCH 3 -C 6 H 4 - 13 12 13 14 136d 4-Cl-C 6 H 4 - 18 15 17 16 196e 4-F-C 6 H 4 - 14 13 14 12 126f 4-Br-C 6 H 4 - 12 12 13 14 136g 4-NH 2 -C 6 H 4 - 15 13 14 13 126h 4-NO 2 -C 6 H 4 - 13 14 15 15 146i 4-OH-C 6 H 4 - 15 19 16 16 17Std n Ampicillin 20 21 21 20 -” Amoxicillin 22 21 22 22 -” Ciprofloxacin 24 22 23 22 -” Norfloxacin 23 23 23 23 -” Greseofulvin - - - - 24160Oxirane…..

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