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EXPERIMENTALSynthesis and therapeutic evaluation of 2-(4-chlorophenyl)-3-(4,5-dihydro-3-(4-methoxyphenyl)-1H-pyrazol-5-yl)-8-methyl-1H-imidazo[1,2-a]pyridine.[A]Preparation of 2-chloro-1-(p-chlorophenyl)ethanone.See on Page No. 37 Part-I (A)[B]Preparation of 2-(p-chlorophenyl)- 8-methyl imidazo[1,2-a]pyridineSee on Page No. 37 Part-I (B)[C]Preparation of 2-(p-chlorophenyl)- 8- methyl imidazo[1,2-a]pyridine-3-carbaldehyde.See on Page No. 37 Part-I (C)[D]Preparation of (2Z)-3-[2-(p-chlorophenyl)-8-methyl imidazo[1,2-a]pyridine-3-yl]-1-aryl prop-2-en-1-one.See on Page No. 38 Part-I (D)[E] Preparation of 2-(4-chlorophenyl)-3-(4,5-dihydro-3-(4-methoxyphenyl)-1H-pyrazol-5-yl)-8-methyl-1H-imidazo[1,2-a]pyridine.A mixture (2z)-3-[2-(4-chlorophenyl)-8-methyl imidazo[1,2-a]pyridine-3-yl]-1-aryl prop-2-en-1-one. (4.02gm,0.01m) and hydrazine hydrate (0.32gm,0.01m) wasrefluxed in methanol in acidic media for 6-8 hrs. The contents were poured on tocrushed ice and product isolated was crystallized from di-chloromethane. Yield 56%(2.6gm); m.p.136 °C; (C 24 H 21 ClN 4 ; Found : C,69.02%;H,4.95%;N,13.35%; Required :C,69.14%;H,5.08%;N,13.44%)TLC solvent system : Ethyl acetate : Hexane ( 4:6)Similarly, other Pyrazoline derivatives have been obtained. The physical dataare recorded in Table No.- 4(B).130Pyrazoline…..