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SYNTHESIS AND THERAPEUTIC EVALUATION OF 6-(2-(4-CHLOROPHENYL)-8-METHYL-1H-IMIDAZO[1,2-a]PYRIDINE-3-YL)-4-ARYL PYRIMIDINE-2(H)-ONE.Oxopyrimidine derivatives synthesized by condensation of (2z)-3-[2-(4-chlorophenyl)-8-methyl imidazo[1,2-a]pyridine-3-yl]-1-aryl prop-2-en-1-one with ureain basic media and methanol as a solvents.CH 3NNClHNORNWhere,R = ArylThe constitution of the synthesised products have been characterized usingelemental analyses, Infrared and 1 H-nuclear magnetic resonance spectroscopy andfurther supported by mass spectroscopy.The products have been screened for their in vitro biological assay likeantibacterial activity towards Gram positive and Gram negative bacterial strainsand antifungal activity towards A. niger at a concentration 40μg. The biologicalactivities of synthesized compounds recorded in table.65Oxopyrimidine…..