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Moreover, methods ( i ) and ( vi ) are also used for the preparation of imidazo[1,2-a]pyrimidines. 10,R ______ 2N NH 2R 1N NH 2R 2H______R N1CHOR 2______RN NH 2 RNC (vi)N 1(iii)R 1RN Cl(i)(ii)XNNNOHNNONR 2HOOOOHRCOORHOOOOH(v)(iv)COORN2NOMECHANISMR 4R 4R 4R R NH R 3RX3 23ONOR+N + 6NNR R 2R R 2R 5 R 662R 1 R RR 5R 1 5 1(I) (II) (III) (IV)The majority of imidazo[1,2-a]pyridine (IV) have been prepared by thereaction of a 2-aminopyridine (I) with a α -halo carbonyl compound (II) gives form(III). Which is further cyclize at room temperature and gives imidazo[1,2-a]pyridine.16Introduction of Chalcone…..