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Download (3100Kb) - Etheses - Saurashtra University

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[F] Antimicrobial activity of 4-(2-(4-chlorophenyl)-8-methyl-1H-imidazo[1,2-a]pyridine-3-yl)-6-aryl pyrimidine-2-amine.Antimicrobial testing was carried out as described in Part- I ExperimentalSection [E] Page No. 38 . The zone of inhibition of the test solution are recorded inTable No.- 2(IIIA).TABLE NO.- 2(IIIA) BIOLOGICAL SCREENING OF (4-(2-(4-CHLOROPHENYL)-8-METHYL-1H-IMIDAZO[1,2-a]PYRIDINE-3-YL)-6-ARYL PYRIMIDINE-2-AMINE.Zone of inhibition in m.mSr.RAntibacterialAntifungalNo.B.coccus S.aureus Pseudo E.coli A.nigermona2(IIIa) C 6 H 5 - 18 17 15 17 152(IIIb) 4-CH 3 -C 6 H 4 - 16 15 13 14 142(IIIc) 4-OCH 3 -C 6 H 4 - 15 14 15 13 122(IIId) 4-Cl-C 6 H 4 - 17 18 18 16 172(IIIe) 4-F-C 6 H 4 - 16 15 14 15 142(IIIf) 4-Br-C 6 H 4 - 14 13 15 14 132(IIIg) 4-NH 2 -C 6 H 4 - 16 14 13 15 122(IIIh) 4-NO 2 -C 6 H 4 - 13 15 14 14 162(IIIi) 4-OH-C 6 H 4 - 20 19 17 16 19Std n Ampicillin 21 21 22 22 -” Amoxicillin 23 23 21 21 -” Ciprofloxacin 24 22 24 23 -” Norfloxacin 22 24 23 23 -” Greseofulvin - - - - 24100Aminopyrimidine…..

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