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EXPERIMENTALSynthesis and therapeutic evaluation of ethyl-6-(2-(4-chlorophenyl)-8- methyl-1H -imidazo[1,2-a]pyridine-3-yl)-4-(4-methoxyphenyl)-2-oxocyclohex-3-ene carboxylate.[A] Preparation of 2-chloro- 1-(p-chlorophenyl)ethanone.See on Page No. 37 Part-I (A)[B]Preparation of 2-(p-chlorophenyl)- 8-methyl imidazo[1,2-a]pyridineSee on Page No. 37 Part-I (B)[C]Preparation of 2- (p-chlorophenyl)- 8-methyl imidazo[1,2-a]pyridine-3-carbaldehyde.See on Page No. 37 Part-I (C)[D]Preparation of (2Z)-3-[2-(p-chlorophenyl)-8-methyl imidazo[1,2-a]pyridine-3-yl]-1-arylprop-2-en-1-one.See on Page No. 38 Part-I (D)[E] Preparation of ethyl-6-(2-(4-chlorophenyl)-8-methyl-1H-imidazo[1,2-a]pyridine-3-yl)-4-(4-methoxyphenyl)-2-oxocyclohex-3-ene-carboxylate.A mixture (2z)-3-[2-(4-chlorophenyl)-8-methyl imidazo[1,2-a] pyridine-3-yl]-1-aryl prop-2-en-1-one.(4.02gm,0.01m) and Ethylacetoacetate (1.30gm,0.01m) wasrefluxed in Acetone for 6-8 hrs.K 2 CO 3 is used as catalyst. The contents were pouredon to crushed ice and product isolated was crystallized from di-chloromethane. Yield59% (3.05gm) ; m.p.163 °C ; (C 30 H 27 ClN 2 O ; Found : C,69.43%;H,5.21%;N,5.35% ;Required : C,69.97%;H,5.28%;N,5.44%)TLC solvent system : Ethyl acetate : Hexane ( 4:6)Similarly, other Cyclohexenone derivatives have been obtained. The physicaldata are recorded in Table No.- 3(B).114Cyclohexenone…..