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Testosterone<br />

Interactions<br />

Drug-drug<br />

• Corticosteroids - May ↑ risk of oedema. Use together cautiously,<br />

especially in patients with cardiac or hepatic disease (Abramovitz,<br />

<strong>2016</strong>),<br />

• Hepatotoxic drugs - May ↑ risk of hepatotoxicity. Monitor liver<br />

function closely (Abramovitz, <strong>2016</strong>),<br />

• Insulin, oral antidiabetics - May ↓ glucose level; may alter dosage<br />

requirements. Monitor glucose level in diabetic patients (Abramovitz,<br />

<strong>2016</strong>).<br />

• Oral anticoagulants - May ↑ sensitivity; may alter dosage requirements.<br />

Monitor PT and international normalized ratio (INR); decrease<br />

anticoagulant dose if necessary (Abramovitz, <strong>2016</strong>),<br />

• Oxyphenbutazone - May ↑ oxyphenbutazone level. Monitor patient<br />

(Abramovitz, <strong>2016</strong>).<br />

Acarbose - Testosterone may ↑ the hypoglycaemic activities of Acarbose.<br />

Acenocoumarol - Testosterone may ↑ the anticoagulant activities of<br />

Acenocoumarol.<br />

Albiglutide - Testosterone may ↑ the hypoglycaemic activities of Albiglutide.<br />

Alogliptin - Testosterone may ↑ the hypoglycaemic activities of Alogliptin.<br />

Betamethasone - Betamethasone may ↑ the fluid retaining activities of<br />

Testosterone.<br />

Bromocriptine - Testosterone may ↑ the hypoglycaemic activities of<br />

Bromocriptine.<br />

C1 Esterase Inhibitor (Human) - Testosterone may ↑ the thrombogenic<br />

activities of C1 Esterase Inhibitor (Human).<br />

Canagliflozin - Testosterone may ↑ the hypoglycaemic activities of<br />

Canagliflozin.<br />

Chlorpropamide - Testosterone may ↑ the hypoglycaemic activities of<br />

Chlorpropamide.<br />

Corticotropin - Corticotropin may ↑ the fluid retaining activities of<br />

Testosterone.<br />

Cortisone acetate - Cortisone acetate may ↑ the fluid retaining activities of<br />

Testosterone.<br />

Cyclosporine - Testosterone may ↑ the hepatotoxic activities of Cyclosporine.<br />

Dapagliflozin - Testosterone may ↑ the hypoglycaemic activities of<br />

Dapagliflozin.<br />

Dehydroepiandrosterone - The risk or severity of adverse effects can be ↑d<br />

when Dehydroepiandrosterone is combined with Testosterone.<br />

Dexamethasone - Dexamethasone may ↑ the fluid retaining activities of<br />

Testosterone.<br />

Dicoumarol - Testosterone may ↑ the anticoagulant activities of Dicoumarol.<br />

108<br />

Version <strong>2016</strong>.3576– – Document LATEXed – 1st May <strong>2016</strong><br />

[git] • Branch: 1.5 @ 26b5e6d • Release: 1.5 (<strong>2016</strong>-05-01)

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