Hormones 2016

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Blood tests eosinophil count. These variations would show as outside the normal range, however they are normal for the situation. It is very useful therefore for biomedical scientists and haematology clinicians to have appropriate clinical details added to the request so that interpretation and best clinical advice can be given on the report where appropriate (unknown, 2013b). Parameter Male Female Haemoglobin g/L 135–180 115–160 WBC x109/L 4.00–11.00 4.00–11.00 Platelets x109/L 150–400 150–400 MCV fL 78–100 78–100 PCV 0.40–0.52 0.37–0.47 RBC x1012/L 4.5–6.5 3.8–5.8 MCH pg 27.0–32.0 27.0–32.0 MCHC g/L 310–370 310–370 RDW 11.5–15.0 11.5–15.0 Neutrophils 2.0–7.5 2.0–7.5 Lymphocytes 1.0–4.5 1.0–4.5 Monocytes 0.2–0.8 0.2–0.8 Eosinophils 0.04–0.40 0.04–0.40 Basophils < 0.1 < 0.1 (O’Sullivan, 2013) Table 17.10 – Adult normal ranges of the full blood count Reference Values for Commonly Ordered Tests Analyte Specimen Conventional SI units units Adrenocorticotropin P 6.0–76.0pg/mL 1.3– (ACTH) 16.7pmol/L Aminotransferases S •Aspartate (AST, 0–35U/L 0–0.58µkat/L SGOT) •Alanine (ALT, 0–35U/L 0–0.58µkat/L SGPT) Ammonia (as P 10–80µg/dL 6–47µmol/L NH 3 ) Amylase S 60–180U/L 0.8–3.2µkat/L Anion gap S 7–16mmol/L 7–16mmol/L Antinuclear S Negative at 1:40 dilution N/A antibody Antithrombin III P •Antigenic 22–39mg/dL 220–390mg/L •Functional 80–130% 0.8–1.30U/L Arterial blood WB, arterial gases (sea level) 464 Version 2016.3576– – Document LATEXed – 1st May 2016 [git] • Branch: 1.5 @ 26b5e6d • Release: 1.5 (2016-05-01)
Blood tests Analyte Specimen Conventional SI units units •Bicarbonate 21–30mEq/L 21–28mmol/L (HCO 3 •Partial pressure 35–45mmHg 4.7–5.9kPa of carbon dioxide (PCO2) •pH 7.38–7.44 7.38–7.44 •Partial pressure 80–100mmHg 11–13kPa of oxygen (PO 2 ) Bilirubin S •Total 0.3–1.0mg/dL 5.1– 17.0µmol/L •Direct 0.1–0.3mg/dL 1.7–5.1µmol/L •Indirect 0.2–0.7mg/dL 3.4– 12.0µmol/L Bleeding time 2.0–9.5min 2.0–9.5min Calcitonin S •Male 3–26pg/mL 3–26ng/L •Female 2–17pg/mL 2–17ng/L Calcium S 9.0–10.5mg/dL 2.2– 2.6mmol/L Calcium, ionized WB 4.5–5.6mg/dL 1.1– 1.4mmol/L Carbon dioxide •Content (sea P 21–30mEq/L 21–30mmol/L level) •Partial pressure WB, arterial 35–45mmHg 4.7–5.9kPa (PCO2) (sea level) Carcinoembryonic S 0–3.4ng/mL 0–3.4µg/L antigen (CEA) Chloride S 98–106mEq/L 98– 106mmol/L Cholesterol P (totals)* •Desirable 6.18mmol/L Low-density P lipoprotein (LDL) cholesterol •Desirable
Page 1 and 2:
Sharon Kimble (S.E.N.,R.G.N.) Hormo
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Contents Leuprorelin Acetate . . .
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Contents Sperm banking . . . . . .
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List of Tables 13.10Reference range
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List of Figures 3.1 Positive and ne
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This document understandable format
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About the author About the author M
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Chapter 2 README FIRST This chapter
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Cyproterone Acetate • nocturia,
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Dydrogesterone Common side-effects
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Estradiol Valerate Cardiovascular
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Goserelin Common side-effects Gastr
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Oestrogel Also known as Regaine, Ro
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Testosterone • oedema, (Abramovit
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Triptorelin Common side-effects Gas
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Chapter 3 Preamble What are hormone
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Side effects want to keep your weig
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What changes will I see? 9 You can
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What changes will I see? Changes to
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What changes will I see? Female-to-
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What changes will I see? Changes to
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What changes will I see? Effect Bod
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Common therapies Oestrogens, conjug
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Drugs used in Female to Male transi
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How oestrogen works DNA’s genetic
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Hormone effects in male→female
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Hormone effects in female→male
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Hormone effects in female→male Ga
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Hormone effects in female→male De
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An overview of the endocrine system
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The major endocrine glands Table 4.
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The Biochemistry of Sex Hormones Fi
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The Biochemistry of Sex Hormones Fi
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Female Genital Anatomy • Epididym
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Female Genital Anatomy of the breas
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Chapter 6 Hormones Estradiol Valera
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Estradiol Valerate If you are signi
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Estradiol Valerate Deferasirox - Th
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Estradiol Valerate Siltuximab - The
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Estradiol Valerate • Nausea, •
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Estradiol Valerate Metabolism - Est
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Oestrogel • Significant increase
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Oestrogel Interactions Drug interac
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Oestrogel • breast swelling, •
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Sandrena • A history of endometri
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Sandrena Breastfeeding Sandrena is
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Sandrena Psychiatric disorders •
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Testosterone Testosterone Administr
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Testosterone being. Examples includ
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Testosterone • Amenorrhoea, • o
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Testosterone Disopyramide - Testost
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Testosterone Effects on Lab Test Re
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Testosterone Schedule IV - Drugs th
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Dutasteride Contains Dutasteride 50
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Dutasteride Pharmacodynamics The on
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Finasteride Effects on Lab Test Res
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Finasteride Pharmacodynamics Finast
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Finasteride Patient Teaching Tell p
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Bicalutamide Pharmacology Bicalutam
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Bicalutamide Hepatic Hepatic side e
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Bicalutamide Cisapride - The serum
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Cyproterone Acetate Administration
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Cyproterone Acetate How it works Th
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Cyproterone Acetate Estradiol - The
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Cyproterone Acetate Repaglinide - T
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Flutamide Note Should be taken afte
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Flutamide Interactions Drug-drug Wa
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Flutamide Contraindications Sensiti
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Goserelin Shelf life Drogenil = 60
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Goserelin Typical dosage Pre-op 3.6
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Goserelin • Sexual dysfunction,
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Goserelin Ciprofloxacin - Goserelin
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Goserelin Itraconazole - Itraconazo
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Goserelin Sorafenib - Sorafenib may
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Leuprorelin Acetate Self-care tips
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Leuprorelin Acetate which leads to
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Leuprorelin Acetate Anagrelide - Le
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Leuprorelin Acetate Flupentixol - L
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Leuprorelin Acetate Mifepristone -
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Leuprorelin Acetate Tacrolimus - Ta
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Triptorelin Triptorelin Alternative
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Triptorelin Insulin Regular - The t
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Triptorelin • anorexia, • gout,
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Triptorelin Distribution The volume
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Triptorelin The suspension vehicle
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Triptorelin • Triptorelin may rai
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Chapter 9 Progestogens Dydrogestero
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Dydrogesterone Pharmacodynamics Dyd
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Dydrogesterone Danaparoid - The the
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Progesterone Contains Cylcogest - P
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Progesterone • Fatigue, • heada
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Progesterone Bosentan - The serum c
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Progesterone Repaglinide - The ther
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Chapter 10 Other useful drugs This
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Emla Cream Slight erythema is frequ
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Emla Cream Typical dosage Electroly
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Minoxidil Warning Do not use near y
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Vaniqa Eflornithine is a prescripti
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Vaniqa Patients may need to continu
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Ethinylestradiol Contains Ethinyles
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Ethinylestradiol • Headache, •
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Ethinylestradiol Bortezomib - The m
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Ethinylestradiol Secobarbital - The
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Medroxyprogesterone Acetate Warning
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Medroxyprogesterone Acetate Route T
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Medroxyprogesterone Acetate Atazana
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Medroxyprogesterone Acetate Insulin
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Medroxyprogesterone Acetate Topiram
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Oestrogens, conjugated Action Mimic
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Oestrogens, conjugated Vaginal - cr
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Oestrogens, conjugated Cyclosporine
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Spironolactone Spironolactone - liq
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Spironolactone Contraindications Hy
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Spironolactone Chlorphenamine - The
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Spironolactone Racepinephrine - Spi
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Spironolactone Warning You should b
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Breast Self Examination can be succ
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Deep Vein Thrombosis - You should a
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Deep Vein Thrombosis Epidemiology
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Osteoporosis Treating a DVT Treatme
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Osteoporosis Your sex - Women are m
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Prostate cancer Height loss and ost
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Testicular Self Examination Figure
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Testicular Self Examination Signs o
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Urinary Tract Infections - UTI’s
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Urinary Tract Infections - UTI’s
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Blood testing What To Expect After
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Blood testing Production of red blo
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Blood testing Proper handling of th
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Blood groups Antigens and antibodie
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Alkaline phosphate - ALP Male Femal
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Blood Glucose High bilirubin levels
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Cholesterol HDL (Good) Cholesterol
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Cholesterol • Stroke, • Serious
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Dehydroepiandrosterone sulphate - D
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Dihydrotestosterone - DHT elevation
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Follicle stimulating hormone - FSH
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High-density lipoprotein - HDL In m
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Low-density lipoprotein - LDL relat
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Liver function tests Indications Th
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Luteinizing hormone - LH Other test
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Oestrogen Test Conventional SI Unit
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Prolactin - PRL Low oestrogen level
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Sex hormone binding globulin - SHBG
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Testosterone Test Conventional SI U
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Thyroxine, free - T4 Raised testost
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Blood, urea and nitrogen - BUN •
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Full Blood Count - FBC Mean corpusc
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Full Blood Count - FBC Lymphocytes
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Full Blood Count - FBC More commonl
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Full Blood Count - FBC High platele
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International Normalised Ratio - IN
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Prostate specific antigen - PSA •
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Prostate specific antigen - PSA Dig
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Thyroid function test - TFT Once ag
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Urine and electrolytes • collect
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Urine and electrolytes Normal Value
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Urine and electrolytes What abnorma
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Urine and electrolytes • Low magn
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Albumin What abnormal results mean
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Chapter 15 Sexually transmitted inf
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Chlamydia It’s passed on from one
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Chlamydia the eyes - if they come i
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Genital herpes Genital herpes Genit
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Genital herpes ⋆ vaginal discharg
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Genital herpes • If urinating is
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Genital warts • Use condoms (male
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Genital warts How will I know if I
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Genital warts Because HPV is spread
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Gonorrhoea Signs and symptoms You m
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Gonorrhoea Sometimes you may be ask
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Hepatitis You can always go back to
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Hepatitis • rimming • fingering
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Hepatitis • as a result of blood-
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Hepatitis • have close contact wi
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Hepatitis • jaundice, • mental
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HIV Why should I get treated? Hepat
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HIV A woman with HIV can transmit t
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HIV • people who have caught anot
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HIV An HIV test should only be done
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HIV • PEP is an emergency measure
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HIV Treatment is usually recommende
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Molluscum contagiosum Molluscum con
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Molluscum contagiosum When to seek
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Molluscum contagiosum The treatment
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Molluscum contagiosum Pulsed-dye la
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Pubic lice What are the signs and s
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Scabies Finding empty eggshells (de
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Scabies Scabies mites can survive o
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Shigella What should I do if I thin
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Syphilis Statistics for 2014 showed
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Syphilis The latent stage can conti
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Syphilis You will be prescribed ano
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Trichomoniasis How is it passed on?
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How to avoid sexually transmitted i
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Condoms Avoid other types of contac
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Condoms • If you are having anal
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Condoms Some men and women are sens
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Condoms Are there different types o
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Condoms Disadvantages • Some coup
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Condoms If you buy condoms online,
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Condoms • Now put your index or m
Page 413 and 414: Condoms Risks There are no serious
Page 415 and 416: Condoms Don’t use lotion or oils
Page 417 and 418: Bacterial vaginosis - BV Women with
Page 419 and 420: Bacterial vaginosis - BV The level
Page 421 and 422: Bacterial vaginosis - BV Things to
Page 423 and 424: Proctitis Proctitis Proctitis is so
Page 425 and 426: Thrush Symptoms • Irritation, bur
Page 427 and 428: Thrush It is very important to take
Page 429 and 430: Thrush Avoid Men should also try to
Page 431 and 432: Urethritis Urethritis Urethritis is
Page 433 and 434: Urethritis Other infections A numbe
Page 435 and 436: Urethritis You will be asked not to
Page 437 and 438: Urethritis NGU and sexually transmi
Page 439 and 440: Urethritis • epididymitis is infl
Page 441 and 442: Vaginal Thrush What to do if you ha
Page 443 and 444: Vaginal Thrush Emollients and antif
Page 445 and 446: Vaginitis • Pain when you wee,
Page 447 and 448: Accessing your health records • A
Page 449 and 450: Accessing your health records An at
Page 451 and 452: Adrenal Fatigue Symptoms said to be
Page 453 and 454: Adrenal Insufficiency Adrenal Insuf
Page 455 and 456: Bio-equivalence Product Presentatio
Page 457 and 458: Bio-equivalence Generic Brand Form
Page 459 and 460: Blood levels Active ingredient Bran
Page 461 and 462: Blood levels Hormone Female Male Bl
Page 463: Blood tests • SHBG, • testoster
Page 467 and 468: Blood tests Analyte Folliclestimula
Page 469 and 470: Blood tests Analyte •Content leve
Page 471 and 472: Body fat Analyte Specimen Conventio
Page 473 and 474: Breast Development Figure 17.2 - Th
Page 475 and 476: Breast disorders • As time passes
Page 477 and 478: Breast disorders Symptom Causes Com
Page 479 and 480: Breast disorders The breast is palp
Page 481 and 482: Breast disorders CBE is usually par
Page 483 and 484: Breast disorders Red flags Certain
Page 485 and 486: Breast disorders Nipple discharge c
Page 487 and 488: Breast disorders Cause Suggestive f
Page 489 and 490: Breast disorders the area around th
Page 491 and 492: Breast disorders Diffuse bilateral
Page 493 and 494: Breast Implants Saline implant rupt
Page 495 and 496: Breast Screening What is the NHS Br
Page 497 and 498: Breast Screening • some cancers a
Page 499 and 500: Coming out A personal experience. W
Page 501 and 502: Consent and Informed Consent Consen
Page 503 and 504: Cycling Hormones? thanks to its ant
Page 505 and 506: E-numbers Drug names Medicines norm
Page 507 and 508: Expiry dates What to do? There are
Page 509 and 510: Further discussion of Vitamin D Fac
Page 511 and 512: Gender expression) related to that
Page 513 and 514: Getting a urine sample or otherwise
Page 515 and 516:
Grapefruit Juice • avoid cocaine,
Page 517 and 518:
Grapefruit Juice Generic Brand Clin
Page 519 and 520:
Heamatological Reference Values Ana
Page 521 and 522:
How to Take Your Tablets. This last
Page 523 and 524:
Implants, Testosterone and Estradio
Page 525 and 526:
Infection? Labial redness variable
Page 527 and 528:
Injections Syringe size Your syring
Page 529 and 530:
Injections 4 Using your "Ampoule Op
Page 531 and 532:
Injections 10 Where appropriate a
Page 533 and 534:
Injections Figure 17.9 - This shows
Page 535 and 536:
Kegel exercises Kegel exercises Fig
Page 537 and 538:
Lactation the muscle for a count of
Page 539 and 540:
Liver damage All products absorbed
Page 541 and 542:
Male pregnancy root), preventing th
Page 543 and 544:
Measuring Your Transition • Measu
Page 545 and 546:
Menopause suggest a specific influe
Page 547 and 548:
Menopause Male menopause Male menop
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Menopause Men normally experience a
Page 551 and 552:
Menopausal symptoms Menopausal symp
Page 553 and 554:
Mood swings and depression See also
Page 555 and 556:
Oestrogen and Alzheimer’s Disease
Page 557 and 558:
Pelvic examination • manual, •
Page 559 and 560:
Pharmacodynamics Pharmacodynamics T
Page 561 and 562:
Premarin Premarin This drug is, sup
Page 563 and 564:
Prescriptions Medical exemptions Pe
Page 565 and 566:
Prostate cancer Prostate cancer The
Page 567 and 568:
Regimes Hormone regimes for transge
Page 569 and 570:
Regimes Name Dosage When taken OR 5
Page 571 and 572:
Regimes Parenterally (i.m. or subcu
Page 573 and 574:
Safety of HRT • Getting older,
Page 575 and 576:
Sexual Health Dementia Evorel [estr
Page 577 and 578:
Sexual Health Mammography Women sho
Page 579 and 580:
Skin care Skin care One of the unfo
Page 581 and 582:
Skin care Sensitive Skin Please not
Page 583 and 584:
Skin care Sanitise your tools Wash
Page 585 and 586:
Skin care • Lemon juice works wel
Page 587 and 588:
Sleep more often reported a variety
Page 589 and 590:
Sleep The stages of NREM sleep and
Page 591 and 592:
Sleep Sleep fragmentation results f
Page 593 and 594:
Smoking and taking hormones Many st
Page 595 and 596:
Stopping hormones prior to surgery
Page 597 and 598:
Stress management Stress management
Page 599 and 600:
Stress management A single episode
Page 601 and 602:
Stress management Reach out - Make
Page 603 and 604:
Stress management Why you react to
Page 605 and 606:
Stress management Reframe your thou
Page 607 and 608:
Stress management • Stressing abo
Page 609 and 610:
Stress management Try aromatherapy
Page 611 and 612:
Stress management your mind as well
Page 613 and 614:
Stretch marks Maintain healthy rela
Page 615 and 616:
Supplies Supplies In the UK Nu-Care
Page 617 and 618:
Testosterone replacement therapy, m
Page 619 and 620:
The real side effects of testostero
Page 621 and 622:
The real side effects of testostero
Page 623 and 624:
The risks of breast cancer One stud
Page 625 and 626:
Thrush "The FDA has reviewed the av
Page 627 and 628:
Transgender Definitions 1 It can’
Page 629 and 630:
Transgender Definitions Cross Dress
Page 631 and 632:
Transgender Definitions Dyke This i
Page 633 and 634:
Transphobia Transwoman A male-to-fe
Page 635 and 636:
Transphobia When referring to trans
Page 637 and 638:
Treatment aims • online abuse,
Page 639 and 640:
Urinary Tract Infections 1 IU 45.5
Page 641 and 642:
Vitality Children Vaginitis usually
Page 643 and 644:
Vitamins Age Folate µg Niacin mg R
Page 645 and 646:
Vitamins Deficiencies - Inadequate
Page 647 and 648:
Vitamins Recommended Dietary Allowa
Page 649 and 650:
Vitamins Food Sources - Avocado, ba
Page 651 and 652:
What is a ’vitamin’? that contr
Page 653 and 654:
Zoff Review the material again - Re
Page 655 and 656:
Books Made In God’s Image: A Reso
Page 657 and 658:
Email This site is strictly for MTF
Page 659 and 660:
Some web sites Some web sites All l
Page 661 and 662:
Chapter 19 Appendix 1 American vs B
Page 663 and 664:
How to evaluate health information
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Page 667 and 668:
Page 669 and 670:
Glossary A | B | C | D | E | F | G
Page 671 and 672:
Glossary cancerous malignant . . .
Page 673 and 674:
Glossary G gastric lavage stomach w
Page 675 and 676:
Glossary lipophilic the ability to
Page 677 and 678:
Glossary spermatogenesis Spermatoge
Page 679 and 680:
Acronyms A | B | C | D | E | F | G
Page 681 and 682:
Acronyms HRT Hormone Replacement Th
Page 683 and 684:
Bibliography [AB, 2011] CellaVision
Page 685 and 686:
Bibliography [Beastall, Ferguson, O
Page 687 and 688:
Bibliography [Burger, 2002] H. G. B
Page 689 and 690:
Bibliography [Corona, Maseroli, Ras
Page 691 and 692:
Bibliography [drugbank, 2014b] 2014
Page 693 and 694:
Bibliography [Fogelman, 1991] L Fog
Page 695 and 696:
Bibliography [Gossman, 2014] MV Gos
Page 697 and 698:
Bibliography [helpguide, 2016b] 201
Page 699 and 700:
Bibliography [L. Johnson, 2014] LE
Page 701 and 702:
Bibliography [Kuper, Mantzoros, Lag
Page 703 and 704:
Bibliography [Lippert, A. O. Mueck,
Page 705 and 706:
Bibliography [mayoclinic, 2014c] 20
Page 707 and 708:
Bibliography [MIMS, 2016a] MIMS 201
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Bibliography [NHS, 2014f] 2014f HIV
Page 711 and 712:
Bibliography [O’Sullivan, 2013] M
Page 713 and 714:
Bibliography [Rasgon, Geist, Kenna,
Page 715 and 716:
Bibliography [Sabon, Cheng, Stommel
Page 717 and 718:
Bibliography [takingcharge, 2010] t
Page 719 and 720:
Bibliography [ucsfhealth, 2009b] 20
Page 721 and 722:
Bibliography [unknown, 2015e] 2015e
Page 723 and 724:
[wikipedia, 2016] 2016 Tanner scale
Page 725 and 726:
Medroxyprogesterone Acetate 215 Oes
Page 727 and 728:
interaction Carbamezapine . . . . .
Page 729 and 730:
depressed mood . . . . . . . . . .
Page 731 and 732:
liver failure . . . . . . . . . . .
Page 733 and 734:
transient erythema . . . . . . . .
Page 735 and 736:
pancreatitis . . . . . . . . . . .
Page 737 and 738:
Vaniqa acne . . . . . . . . . . . .
Page 739 and 740:
Aminophylline Cyproterone Acetate .
Page 741 and 742:
Capromab Bicalutamide . . . . . . .
Page 743 and 744:
Nelfinavir . . . . . . . . . . . .
Page 745 and 746:
Edetic Acid Cyproterone Acetate . .
Page 747 and 748:
C1 Esterase Inhibitor (Human) 213 C
Page 749 and 750:
Leuprorelin Acetate . . . . . . . 1
Page 751 and 752:
Propofol . . . . . . . . . . . . .
Page 753 and 754:
Progesterone. . . . . . . . . . . .
Page 755 and 756:
Maprotiline . . . . . . . . . . . .
Page 757 and 758:
Glimepiride . . . . . . . . . . . .
Page 759 and 760:
Bicalutamide . . . . . . . . . . .
Page 761 and 762:
Goserelin . . . . . . . . . . . . .
Page 763 and 764:
Saxagliptin Cyproterone Acetate . .
Page 765 and 766:
Tasimelteon Cyproterone Acetate . .
Page 767 and 768:
Goserelin . . . . . . . . . . . . .
Page 769 and 770:
Index of STI’s A Avoidance . . .
Page 771 and 772:
Curettage . . . . . . . . . . . . .
Page 773 and 774:
General Index A Accessing someone e
Page 775 and 776:
What happens? . . . . . . . . . . .
Page 777 and 778:
Importing hormones. . . . . . . . .
Page 779 and 780:
S Safety of our regimes . . . . . .
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