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High-density lipoprotein - HDL<br />

In men, FSH serves to induce spermatogonium development. Determination<br />

of the FSH concentration is used in the elucidation of dysfunctions<br />

within the hypothalamus-pituitary-gonads system. Depressed<br />

gonadotropin levels in men occur in azoospermia (Runnebaum and Rabe,<br />

1994), (M. R. Johnson et al., 1993), (Schmidt-Mathiesen, 1992), (Scott et al.,<br />

1989).<br />

High-density lipoprotein - HDL<br />

HDL cholesterol is used in the assessment of coronary or other vascular<br />

pathology risk (medscape, 2014b).<br />

Instructions<br />

You should fast at least 12–14 hours before the blood is taken (medscape,<br />

2014b).<br />

Gender<br />

Males<br />

Females<br />

Ranges<br />

> 55 mg/dL<br />

> 65 mg/dL<br />

Table 13.8 – Reference ranges for high-density lipoprotein<br />

Interpretation<br />

Increased levels<br />

High-density lipoprotein cholesterol (High-density lipoprotein cholesterol<br />

(HDL-C)) levels are increased in the following conditions -<br />

• Hyperalphalipoproteinemia,<br />

• Regular physical activity or exercise,<br />

• Chronic liver disease,<br />

• Weight loss (Williamson, Snyder, and Wallach, 2011).<br />

HDL-C levels are increased in association with moderate ethanol consumption,<br />

insulin, and oestrogen (Williamson, Snyder, and Wallach, 2011).<br />

Additionally, regular aerobic exercise, smoking cessation, decrease in body<br />

mass index, and statin therapy (mild) increase HDL-C levels. Statins or<br />

HMG-CoA reductase inhibitors modestly increase HDL-C levels. The mild<br />

rise in HDL-C levels from these drugs may be related to inhibition of rho-<br />

283<br />

Version <strong>2016</strong>.3576– – Document LATEXed – 1st May <strong>2016</strong><br />

[git] • Branch: 1.5 @ 26b5e6d • Release: 1.5 (<strong>2016</strong>-05-01)

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