24.05.2016 Views

Hormones 2016

Hormones-2016

Hormones-2016

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

Male pregnancy<br />

root), preventing the necessary nourishment for the hair getting through<br />

for proper growth. DHT causes the hair follicles to shrink. The growing<br />

"anagen" stage of the hair is shortened and the resting "telogen" stage is<br />

extended. Eventually these hairs stop growing.<br />

Androgenetic alopecia (AGA; male-pattern baldness) is a hereditary and<br />

androgen-dependent progressive thinning of the scalp hair that follows<br />

a defined pattern (Stanczyk, 2006). While the genetic involvement is<br />

pronounced but poorly understood, major advances have been achieved<br />

in understanding the principal elements of androgen metabolism that are<br />

involved. DHT may be related to baldness. High concentrations of 5<br />

alpha-reductase have been found in frontal scalp and genital skin and<br />

androgen-dependent processes are predominantly due to the binding of<br />

DHT to the androgen receptor (AR). Since the clinical success of treatment<br />

of AGA with modulators of androgen metabolism or hair growth promoters<br />

is limited, sustained microscopic follicular inflammation with connective<br />

tissue remodeling, eventually resulting in permanent hair loss, is considered<br />

a possible cofactor in the complex etiology of AGA (mayomedical, <strong>2016</strong>).<br />

Male pregnancy<br />

Male pregnancy is the carrying of one or more embryos or foetuses<br />

by the male of any species inside their bodies. The majority of all<br />

pregnancies in the animal kingdom are carried by female organisms. In<br />

most heterogamous species 135 , the males produce the spermatazoa 136 and<br />

rarely host the zygote 137 .<br />

Speculation on inducing pregnancy in men<br />

British physician Robert Winston speculates that it may be possible to<br />

surgically induce abdominal ectopic pregnancy in men (unknown, 1999). In<br />

his book "The IVF Revolution", Winston speculates that an embryo could<br />

be implanted in a man’s abdomen – with the placenta attached to an internal<br />

organ such as the bowel – and that the baby would later be delivered by<br />

Caesarean section. However, other experts expressed great concerns about<br />

the safety of such a procedure.<br />

135 In reproductive biology, heterogamy or heterogamous is often used as a synonym of<br />

heterogametic, meaning the presence of two unlike chromosomes in a sex. For example,<br />

XY males and ZW females are called the heterogamous sex<br />

136 one of the minute, usually actively motile gametes in semen, which serve to fertilize<br />

the ovum; a mature male reproductive cell<br />

137 the cell produced by the union of two gametes, before it undergoes cleavage<br />

541<br />

Version <strong>2016</strong>.3576– – Document LATEXed – 1st May <strong>2016</strong><br />

[git] • Branch: 1.5 @ 26b5e6d • Release: 1.5 (<strong>2016</strong>-05-01)

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!