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Hormones 2016

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Testosterone<br />

Overdose<br />

The acute intramuscular toxicity of Sustanon 100 or 250 is very low.<br />

Priapism in men is a symptom of chronic overdose. If this occurs, Sustanon<br />

treatment should be interrupted and, after disappearance of the symptom,<br />

be resumed at a lower dose.<br />

Andropatch = This is not likely due to the mode of administration.<br />

Serum testosterone has a half-life of 70 minutes and therefore falls rapidly<br />

once the Andropatch 2.5mg or 5mg Systems are removed. Only one case of<br />

acute testosterone overdose following an injection has been reported in the<br />

literature. This was a case of a cerebrovascular accident in a patient with a<br />

high plasma testosterone concentration of 114 ng/ml (395 nmol/l). It would<br />

be most unlikely that such plasma testosterone concentrations be achieved<br />

using the transdermal route (emc, <strong>2016</strong>).<br />

Note<br />

In the United States, the possession and distribution of anabolic steroids,<br />

such as testosterone, is a felony offense unless prescribed by a physician<br />

for medical use. The Steroid Control Act of 1990 made the use of<br />

anabolic steroids for the purpose of performance enhancement illegal. This<br />

legislation would be enhanced and strengthened by the Steroid Control Act<br />

of 2004 and again in 2014 under the Designer Steroid Control Act of 2014.<br />

Failure to abide by the guidelines enacted by the aforementioned legislation<br />

can lead to severe punishments including fines and prison sentences. Such<br />

punishments can range from charges of simple possession, to distribution<br />

and the intent to distribute.<br />

As the federal government’s war on steroids has increasingly gained fire,<br />

the enforcement of the legislation has followed suit with many otherwise<br />

law-abiding citizens finding themselves in the presence of the courts in<br />

disastrous ways. U.S. federal law classifies anabolic androgenic steroids,<br />

and testosterone, as Schedule III controlled substances. Schedule III<br />

classification puts anabolic steroids in the same category as barbiturates and<br />

LSD precursors.<br />

In the U.S. there are five classes of scheduled drugs and they are as follows:<br />

Schedule I - Drugs with no viable medical purpose and that have a high<br />

rate of both dependency and abuse that can in turn lead to severe<br />

physical damage.<br />

Schedule II - Drugs that while possessing a viable medical purpose have<br />

a high potential for abuse and dependency and can in turn lead to<br />

severe physical damage.<br />

Schedule III - Drugs that possess a viable medical purpose but do carry<br />

with them the risk of dependency and physical damage but to a lesser<br />

extent than compared to Schedule II drugs.<br />

112<br />

Version <strong>2016</strong>.3576– – Document LATEXed – 1st May <strong>2016</strong><br />

[git] • Branch: 1.5 @ 26b5e6d • Release: 1.5 (<strong>2016</strong>-05-01)

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