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Hormones 2016

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Full Blood Count - FBC<br />

White blood cell differential<br />

The results indicate the relative percentage and actual numbers of each type<br />

of white blood cell that is present.<br />

Neutrophils can increase in response to bacterial infection, inflammatory<br />

disease, steroid medication, or more rarely leukaemia. Decreased<br />

neutrophil levels may be the result of severe infection, liver disease,<br />

enlarged spleens or other conditions, such as responses to various<br />

medications or chemotherapy.<br />

Eosinophils can increase in response to allergic disorders, inflammation of<br />

the skin, and parasitic infections. They can also occur in response to some<br />

infections or to various bone marrow malignancies.<br />

Basophils can increase in cases of leukaemia, long-standing inflammation,<br />

the presence of a hypersensitivity reaction to food, or radiation therapy.<br />

Lymphocytes can increase in cases of bacterial or especially viral infection,<br />

leukaemia, lymphoma and in people with underactive or absent spleens.<br />

Decreased lymphocyte levels are common in later life but can also be due<br />

to steroid medication, stress, lupus, and human immunodeficiency virus<br />

(HIV) infection.<br />

Monocyte levels can increase in certain leukaemias, in response to infection<br />

of all kinds as well as to inflammatory disorders. Decreased monocyte levels<br />

can indicate bone marrow injury or failure and some forms of leukaemia -<br />

especially "hairy cell leukaemia" .<br />

Neutrophils<br />

- engulf bacteria and cellular debris. An increase in the number of<br />

neutrophils occurs in acute infections, certain malignant neoplastic diseases,<br />

and some other disorders.<br />

Eosinophils<br />

- normally about 1–3% of the total white blood cell count, are believed to<br />

function in allergic responses and in resisting some infections.<br />

Basophils<br />

- normally constitute 1% or less of the total white blood cell count but may<br />

increase or decrease in certain diseases.<br />

304<br />

Version <strong>2016</strong>.3576– – Document LATEXed – 1st May <strong>2016</strong><br />

[git] • Branch: 1.5 @ 26b5e6d • Release: 1.5 (<strong>2016</strong>-05-01)

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