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Hormones 2016

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Progesterone<br />

• skin rashes,<br />

• hives,<br />

• acne (WebMD, 2014e),<br />

• itching (medlineplus, 2015b).<br />

Respiratory<br />

• shortness of breath,<br />

• difficulty breathing,<br />

• difficulty swallowing,<br />

• swelling of the face, throat,<br />

tongue,<br />

• lips, eyes, hands,<br />

• feet, ankles, or lower legs<br />

(medlineplus, 2015b).<br />

Musculoskeletal<br />

• leg swelling or pain, • weakness or numbness of<br />

an arm or leg (medlineplus,<br />

2015b).<br />

Interactions/incompatibilities<br />

The metabolism of progesterone by human liver microsomes was inhibited<br />

by ketoconazole (IC50

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