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182<br />
ABDOMINAL ULTRASOUND<br />
Ultrasound may also be used to diagnose<br />
acquired cystic kidney disease in long-term dialysis<br />
patients (see above).<br />
RENAL TRAUMA<br />
The severity of trauma to the kidney may vary significantly<br />
and therefore a range of findings can be<br />
seen with ultrasound. A direct injury can rupture<br />
the kidney. This will result in blood and/or urine<br />
leaking out into the perinephric space. The nature<br />
of the fluid can be determined by ultrasound<br />
guided aspiration. A large urinoma or haematoma<br />
may be drained percutaneously. The main renal<br />
vessels may also be damaged, causing lack of perfusion<br />
(see Chapter 10).<br />
Causes of haematuria are listed in Table 7.3.<br />
RENAL TRANSPLANTS<br />
Although there are a number of treatment choices<br />
for patients with renal failure including peritoneal<br />
and haemodialysis, undoubtedly the treatment of<br />
choice is renal transplantation.<br />
From the very early days of Carrel’s experimental<br />
attempts at transplantation in the 1900s<br />
(resulting in the Nobel Prize of 1912 26 ), to the<br />
un-immunosuppressed allografting of the 1950s,<br />
the more successful and encouraging outcome of<br />
twin to twin transplants, 27 a better understanding<br />
of tissue rejection and the introduction of azathioprine<br />
and steroid in 1963, 28 and more specifically<br />
ciclosporin A by Calne in the 1970s, 29 have all<br />
Table 7.3<br />
Causes of haematuria<br />
● Urinary tract infection<br />
● Stones<br />
● Neoplasm (renal cell or transitional cell carcinoma in<br />
the kidney, ureter or bladder)<br />
● Prostatic pathology (benign hypertrophy or carcinoma)<br />
● Renal cyst haemorrhage<br />
● Papillary necrosis<br />
● Glomerulonephritis<br />
● Trauma<br />
● Tuberculosis<br />
● Renal infarct<br />
contributed immensely to slow but positive<br />
progress in this field. Improvements in surgical<br />
technique, newer, more effective and less toxic<br />
anti-rejection therapy, the routine use of ultrasound<br />
in the 1970s and then Doppler a decade<br />
later, and the development of interventional radiology<br />
have all combined to make this the successful<br />
operation and clinical outcome we now take so<br />
much for granted.<br />
Although many different imaging modalities are<br />
available, ultrasound is the single most useful<br />
investigation in the postoperative monitoring of<br />
the transplant. Amongst its many roles, it is sensitive<br />
to early PCS dilatation, can be used to guide<br />
biopsy procedures and to guide the drainage of<br />
fluid collections and placement of nephrostomy<br />
tubes.<br />
An early, baseline scan is an essential part of the<br />
postoperative management, and serial scans are to<br />
be recommended.<br />
Normal anatomy<br />
Most renal transplants are heterotopic, that is they<br />
are placed in addition to the diseased, native kidneys,<br />
which remain in situ.<br />
The transplanted organ is usually positioned in<br />
the iliac fossa anterior to the psoas and iliacus muscles.<br />
It lies outside the peritoneal cavity.<br />
Within the UK the majority of transplanted kidneys<br />
are cadaveric, and are harvested with their<br />
main vessels intact, which are then anastomosed to<br />
the recipient iliac artery and vein.<br />
Normal ultrasound appearances<br />
The transplanted kidney is particularly amenable to<br />
ultrasonic investigation; its position relatively near<br />
to the skin surface allows a high frequency transducer<br />
(5 MHz) to be used for better detail. For<br />
visualization of the vasculature or origins of the<br />
transplant vessels a 3.5–4.0MHz probe is normally<br />
required.<br />
The ultrasonic appearances of the transplant kidney<br />
are the same as expected for a native kidney,<br />
allowing for the higher resolution [Fig. 7.24]. The<br />
transplant kidney should be assessed in the same<br />
way as the native organ, that is in two planes.<br />
Features to be observed include: