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PATHOLOGY OF THE LIVER AND PORTAL VENOUS SYSTEM 81<br />

Figure 4.3 Large, infected hepatic cyst containing lowlevel<br />

echoes.<br />

Another uncommon cause of a cystic lesion in the<br />

liver is a cystadenoma—a benign epithelial tumour.<br />

These have the potential to turn malignant, forming<br />

a cystadenocarcinoma. Close monitoring with ultrasound<br />

will demonstrate a gradual increase in size,<br />

changes in the appearances of the wall of the cyst,<br />

such as thickening or papillary projections, and<br />

internal echoes in some cases, which may arouse<br />

suspicion. A diagnostic aspiration may be performed<br />

under ultrasound guidance, and the fluid may contain<br />

elevated levels of carcinoembryonic antigen if<br />

malignant. 2 Cystadenomas are usually surgically<br />

removed due to their malignant potential (Fig. 4.4).<br />

Rarely, cystic lesions in the liver may be due to<br />

other causes. These include pancreatic pseudocyst<br />

(within an interlobular fissure) in patients with<br />

acute pancreatitis or mucin-filled metastatic<br />

deposits in primary ovarian cancer.<br />

An arteriovenous malformation, a rare finding<br />

in the liver, may look like a septated cystic lesion.<br />

Doppler, however, will demonstrate flow throughout<br />

the structure.<br />

Polycystic liver<br />

There is a fine dividing line between a liver which<br />

contains multiple simple cysts and polycystic liver<br />

A<br />

B<br />

Figure 4.4 (A) Large cystadenoma containing echoes and a septum. The cyst was large enough to cause obstructive<br />

jaundice—the patient’s presenting symptom. The diagnosis was made by ultrasound-guided aspiration. This cyst had<br />

developed into a cystadenocarcinoma after 2 years. (B) A cystadenocarcinoma in a young woman presenting with<br />

altered liver function tests (LFTs). The cyst contains echoes and some solid material.

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