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206<br />
ABDOMINAL ULTRASOUND<br />
areas of necrosis within them. Most are benign, but<br />
5–10% are malignant. It presents on a background<br />
of episodic, severe hypertension and the urine contains<br />
catecholamines. (Although this is also a feature<br />
of adrenal neuroblastoma, the latter is<br />
predominantly a childhood tumour.) These lesions<br />
should be treated with great care—vigorous palpation<br />
may precipitate a severe hypertensive episode<br />
and biopsy should therefore be avoided.<br />
Although most phaeochromocytomas arise in the<br />
adrenal glands, and are therefore demonstrable on<br />
ultrasound, those arising in the sympathetic chain<br />
may be obscured by bowel gas and are not possible<br />
to exclude on ultrasound (Fig. 8.8D, E). If there<br />
remains biochemical evidence of phaeochromocytoma<br />
in the presence of normal adrenal glands,<br />
a Meta-Iodobenzylguanidine isotope scan will<br />
demonstrate increased activity in a phaeochromocytoma<br />
and CT scan can then be targeted to the<br />
appropriate area.<br />
Phaeochromocytomas are also associated with<br />
von Hippel–Lindau syndrome.<br />
Adrenal carcinoma<br />
Primary adrenal carcinomas are rare in the adult.<br />
They are commonly endocrinologically inactive in<br />
adults, and therefore tend to present late when<br />
they are quite large. They may invade the IVC and<br />
metastasize to the liver. Surgical removal of<br />
tumours in the absence of liver metastases has a<br />
good prognosis 9 and, in patients with metastases,<br />
radiofrequency ablation of the adrenal mass may<br />
have some benefit in prolonging survival. 10<br />
GASTROINTESTINAL (GI) TRACT<br />
Contrast radiographic investigations, including CT,<br />
are generally accepted as the methods of choice for<br />
investigating diseases of the GI tract. Although ultrasound<br />
is not considered a primary tool in the investigation<br />
of bowel lesions, as the gas-filled lumen<br />
makes visualization difficult in many cases, ultrasound<br />
is remarkably successful in diagnosing GI<br />
tract pathology in the hands of an experienced operator.<br />
GI tract ultrasound can be time-consuming,<br />
but a wealth of information can be obtained with a<br />
high-frequency linear probe in a symptomatic<br />
patient. Considerable diagnostic benefit has been<br />
shown for careful, targeted, percutaneous ultrasound<br />
of the large and small GI tract using high-frequency<br />
transducers. 11<br />
It is important to be aware of the variable ultrasound<br />
appearances of normal bowel, as it may be<br />
responsible for mimicking other pathology.<br />
Normal bowel is frequently difficult to examine on<br />
ultrasound as the gas-filled lumen reflects the<br />
sound, requiring careful compression techniques.<br />
Abnormal bowel is particularly accessible to ultrasound,<br />
however. A fluid-filled lumen also make<br />
easy the demonstration of valvulae conniventes of<br />
the small bowel and haustra of the large colon.<br />
Oesophagus and stomach<br />
The oesophagus is not usually accessible to percutaneous<br />
ultrasound; however, the lower end can be<br />
demonstrated as it passes through the diaphragm in<br />
the midline, just anterior to the aorta (Fig. 8.9A).<br />
Its normal appearances should not be confused with<br />
a mass. Occasionally, ultrasound demonstrates the<br />
thickened wall associated with an oesophageal carcinoma<br />
involving the lower oesophagus (Fig. 8.9B).<br />
Endoscopic ultrasound (EUS), with its high frequency<br />
and proximity to the relevant structures, is<br />
able to demonstrate the layers of the gut wall, and<br />
to demonstrate pathology and accurately stage<br />
malignant disease in both the oesophagus and<br />
stomach, and also to guide invasive procedures. 12,13<br />
Barium X-ray studies are still the first-line investigation<br />
of choice for many potential GI tract conditions;<br />
however, endoscopy is regarded as the<br />
gold standard for investigating the lining of the<br />
stomach and duodenum and can be combined<br />
with biopsy when necessary. Although percutaneous<br />
ultrasound has had modest success in revealing<br />
stomach masses if the stomach is filled with<br />
water, 14 it can never replace endoscopy. However,<br />
if such lesions are discovered, this helps to direct<br />
subsequent radiological management (Fig. 8.10).<br />
Appendix<br />
Acute appendicitis is a common diagnosis on<br />
admission to the casualty department with right<br />
lower abdominal pain. However around 15–25% of