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206<br />

ABDOMINAL ULTRASOUND<br />

areas of necrosis within them. Most are benign, but<br />

5–10% are malignant. It presents on a background<br />

of episodic, severe hypertension and the urine contains<br />

catecholamines. (Although this is also a feature<br />

of adrenal neuroblastoma, the latter is<br />

predominantly a childhood tumour.) These lesions<br />

should be treated with great care—vigorous palpation<br />

may precipitate a severe hypertensive episode<br />

and biopsy should therefore be avoided.<br />

Although most phaeochromocytomas arise in the<br />

adrenal glands, and are therefore demonstrable on<br />

ultrasound, those arising in the sympathetic chain<br />

may be obscured by bowel gas and are not possible<br />

to exclude on ultrasound (Fig. 8.8D, E). If there<br />

remains biochemical evidence of phaeochromocytoma<br />

in the presence of normal adrenal glands,<br />

a Meta-Iodobenzylguanidine isotope scan will<br />

demonstrate increased activity in a phaeochromocytoma<br />

and CT scan can then be targeted to the<br />

appropriate area.<br />

Phaeochromocytomas are also associated with<br />

von Hippel–Lindau syndrome.<br />

Adrenal carcinoma<br />

Primary adrenal carcinomas are rare in the adult.<br />

They are commonly endocrinologically inactive in<br />

adults, and therefore tend to present late when<br />

they are quite large. They may invade the IVC and<br />

metastasize to the liver. Surgical removal of<br />

tumours in the absence of liver metastases has a<br />

good prognosis 9 and, in patients with metastases,<br />

radiofrequency ablation of the adrenal mass may<br />

have some benefit in prolonging survival. 10<br />

GASTROINTESTINAL (GI) TRACT<br />

Contrast radiographic investigations, including CT,<br />

are generally accepted as the methods of choice for<br />

investigating diseases of the GI tract. Although ultrasound<br />

is not considered a primary tool in the investigation<br />

of bowel lesions, as the gas-filled lumen<br />

makes visualization difficult in many cases, ultrasound<br />

is remarkably successful in diagnosing GI<br />

tract pathology in the hands of an experienced operator.<br />

GI tract ultrasound can be time-consuming,<br />

but a wealth of information can be obtained with a<br />

high-frequency linear probe in a symptomatic<br />

patient. Considerable diagnostic benefit has been<br />

shown for careful, targeted, percutaneous ultrasound<br />

of the large and small GI tract using high-frequency<br />

transducers. 11<br />

It is important to be aware of the variable ultrasound<br />

appearances of normal bowel, as it may be<br />

responsible for mimicking other pathology.<br />

Normal bowel is frequently difficult to examine on<br />

ultrasound as the gas-filled lumen reflects the<br />

sound, requiring careful compression techniques.<br />

Abnormal bowel is particularly accessible to ultrasound,<br />

however. A fluid-filled lumen also make<br />

easy the demonstration of valvulae conniventes of<br />

the small bowel and haustra of the large colon.<br />

Oesophagus and stomach<br />

The oesophagus is not usually accessible to percutaneous<br />

ultrasound; however, the lower end can be<br />

demonstrated as it passes through the diaphragm in<br />

the midline, just anterior to the aorta (Fig. 8.9A).<br />

Its normal appearances should not be confused with<br />

a mass. Occasionally, ultrasound demonstrates the<br />

thickened wall associated with an oesophageal carcinoma<br />

involving the lower oesophagus (Fig. 8.9B).<br />

Endoscopic ultrasound (EUS), with its high frequency<br />

and proximity to the relevant structures, is<br />

able to demonstrate the layers of the gut wall, and<br />

to demonstrate pathology and accurately stage<br />

malignant disease in both the oesophagus and<br />

stomach, and also to guide invasive procedures. 12,13<br />

Barium X-ray studies are still the first-line investigation<br />

of choice for many potential GI tract conditions;<br />

however, endoscopy is regarded as the<br />

gold standard for investigating the lining of the<br />

stomach and duodenum and can be combined<br />

with biopsy when necessary. Although percutaneous<br />

ultrasound has had modest success in revealing<br />

stomach masses if the stomach is filled with<br />

water, 14 it can never replace endoscopy. However,<br />

if such lesions are discovered, this helps to direct<br />

subsequent radiological management (Fig. 8.10).<br />

Appendix<br />

Acute appendicitis is a common diagnosis on<br />

admission to the casualty department with right<br />

lower abdominal pain. However around 15–25% of

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