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THE RETROPERITONEUM AND GASTROINTESTINAL TRACT 203<br />

A<br />

B<br />

Figure 8.6 (A) Compression of the IVC by a large liver metastasis caused Budd–Chiari syndrome. This has been<br />

relieved by the insertion of a metal stent into the IVC (arrows) under angiographic control. (B) Unusual case of a<br />

small leiomyosarcoma in the IVC found incidentally. Normally they are larger, presenting with symptoms of IVC<br />

obstruction.<br />

Pathology of the adrenal glands<br />

Adenoma<br />

Small (less than 3 cm) solid adrenal nodules are a<br />

common, incidental finding in non-symptomatic<br />

patients (Fig. 8.8A).<br />

Benign, non-hyperfunctioning adenomas account<br />

for the majority of adrenal nodules, and are of no clinical<br />

significance. Their incidence increases with age<br />

and they are present in around 2% of adult autopsies.<br />

Small nodules in asymptomatic patients generally<br />

require no further action, but endocrine function<br />

may be evaluated to rule out a functioning mass.<br />

A hyperfunctioning adenoma (a determination<br />

made by evaluation of the endocrine function),<br />

although an essentially benign mass, usually<br />

requires surgical resection.<br />

As a solitary abdominal finding in a patient with<br />

no relevant clinical history, it is generally safe to<br />

assume a small adrenal nodule requires no further<br />

action. However, because it is not possible to distinguish<br />

benign, incidental nodules from other<br />

forms of more serious pathology, incidental nodules<br />

of greater than 4 cm should be investigated<br />

further to confirm their benign nature. 8 Non-functioning<br />

adenomas will remain stable in size on<br />

ultrasound follow-up.<br />

Metastasis<br />

The adrenal glands are a common site for metastases,<br />

particularly from lung, breast and bowel cancer.<br />

Although frequently accompanied by liver<br />

metastases, they may be present in the absence of<br />

any other obvious abdominal deposits, and therefore<br />

the adrenal glands should routinely be examined<br />

when staging malignant disease.<br />

The adrenal glands are also commonly involved<br />

in non-Hodgkin’s lymphoma.<br />

Like adenomas, they are often small, welldefined<br />

and hypoechoic on ultrasound (Fig. 8.8B).<br />

It is not possible to differentiate between benign<br />

adenoma and metastasis on the ultrasound appearances<br />

alone, but a small adrenal mass in the<br />

absence of a known primary carcinoma is likely to<br />

be benign, and will remain stable on follow-up. A<br />

solitary adrenal mass in the presence of known carcinoma<br />

requires biopsy for diagnosis.<br />

Adrenal cysts<br />

Simple cysts are uncommon in the adrenal gland,<br />

but are easily differentiated from solid lesions with<br />

ultrasound. Some cysts may be the sequelae of previous<br />

haemorrhage, but most are simple, epithelial<br />

cysts.

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