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220<br />

ABDOMINAL ULTRASOUND<br />

peak incidence before 5 years of age. It occurs in<br />

various sites throughout the body.<br />

Other causes of focal liver lesions<br />

Liver metastases may occur from most paediatric<br />

malignancies, particularly neuroblastoma, rhabdomyosarcoma<br />

and Wilms’ tumour (p. 229).<br />

Leukaemia and lymphoma may also cause focal<br />

defects in the liver. Liver involvement may be manifested<br />

by hepatomegaly with normal liver texture,<br />

a non-specific sign, or by diffuse coarsened liver<br />

texture with or without hepatomegaly.<br />

Haemangioendothelioma<br />

Vascular tumours account for most benign liver<br />

tumours in childhood, with haemangioendotheliomas<br />

being seen more frequently than cavernous<br />

haemangiomas. Although haemangioendothelioma<br />

may be asymptomatic, infants generally present<br />

before the age of 6 months with an abdominal<br />

mass, respiratory distress, anaemia and cardiac failure,<br />

caused by the shunting of blood from the<br />

aorta through the tumour. Large tumours may<br />

bleed spontaneously, resulting in haemoperitoneum.<br />

They may present with jaundice and<br />

increased transaminase levels and 50% of children<br />

also have cutaneous haemangioma. 10<br />

These tumours are generally multiple, of varying<br />

echogenicity and may have a complex echotexture<br />

due to thrombus, calcifications and internal septations<br />

(Fig. 9.3B). The vascular nature of these<br />

lesions is demonstrated by a large coeliac axis and<br />

marked decrease in the size of the aorta below the<br />

origin of the coeliac axis. The main differential<br />

diagnosis of multiple haemangioendothelioma is<br />

from metastatic liver disease, particularly from disseminated<br />

neuroblastoma.<br />

Although most asymptomatic paediatric haemangioendotheliomas<br />

regress spontaneously, those<br />

complicated by cardiac failure require active treatment.<br />

Steroids may be administered and serial<br />

ultrasound scans may be used to monitor the gradual<br />

resolution of the lesion. Angiographic<br />

embolization or surgical ligation of the major<br />

feeding vessels of the hepatic artery may be necessary<br />

in severe cases that fail to respond to steroid<br />

therapy.<br />

PANCREAS<br />

Normal appearances<br />

The acoustic characteristics of the pancreas vary<br />

with age. Pancreatic echogenicity is quite variable<br />

and is occasionally hypoechoic in neonates compared<br />

with the adult gland. In older children<br />

echogenicity is equal to or slightly greater than<br />

that of the liver. The pancreas is relatively larger in<br />

young children than in adults, gradually increasing<br />

with age, reaching adult size in late teens. 11 The<br />

pancreatic duct is often visualized but should not<br />

be greater than 2 mm in width. The relative<br />

hypoechogenicity and relatively larger size of the<br />

normal pancreas in childhood should not be misinterpreted<br />

as a sign of probable pancreatitis when<br />

scanning a child with abdominal pain (Fig. 9.4).<br />

Pathology of the pancreas<br />

Pancreatic abnormalities are relatively uncommon<br />

in childhood. Most ultrasound abnormalities are<br />

the result of infiltrative processes associated with<br />

other syndromes or diseases (Table 9.1). Focal<br />

pancreatic lesions are rare.<br />

Ultrasound is an ideal investigation for evaluating<br />

the paediatric pancreas, as a high-frequency<br />

Figure 9.4 Normal pancreas in a 13-year-old girl—<br />

relatively hypoechoic and bulky in comparison with the<br />

adult gland.

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