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THE PAEDIATRIC ABDOMEN 229<br />

Table 9.3<br />

Imaging the paediatric renal tract<br />

Ultrasound<br />

Contrast sonocystography<br />

Diuretic renogram (dynamic) Tc 99m MAG3<br />

Radionuclide cystography (dynamic)<br />

Direct (via catheter or suprapubic injection<br />

of isotope into the bladder) or indirect<br />

(following diuretic renogram)<br />

Cortical scintigraphy (static)—Tc 99m DMSA<br />

Intravenous urography (IVU)<br />

Micturating cystourethrogram<br />

Plain X-ray<br />

CT<br />

MRI<br />

First-line investigation in all cases. Excellent structural detail<br />

Limited sensitivity for duplex kidneys, reflux, ureteral pathology and small<br />

scars<br />

Monitoring of disease progression<br />

Monitoring of treatment<br />

Alternative to X-ray or radionuclide cystography. Poor structural detail,<br />

unsuitable for the demonstration of urethral anomalies<br />

Outlines the pelvicalyceal system. Diagnosis of obstruction and relative renal<br />

function by analysis of excretion curves<br />

Diagnosis of reflux<br />

Demonstrates uptake in the renal cortex<br />

Superior detection of renal scarring in vesicoureteric reflux and acute<br />

pyelonephritis<br />

Demonstration of congenital anomalies, e.g. ectopic or solitary kidney<br />

Analysis of differential renal function<br />

Limited use in children<br />

Assessment of level of ureteric obstruction<br />

Assessment of congenital anomalies, e.g. ectopic ureters and duplex kidney<br />

Postoperative evaluation<br />

Accurate diagnosis of reflux, polyps, diverticula, strictures and urethral<br />

anomalies, but involving a significant radiation dose<br />

Some calculi, mainly those in the ureter<br />

Of limited value in paediatric renal work-up<br />

May show gross spinal anomalies<br />

Reserved mainly for confirmation and staging of malignant tumours, due to<br />

significant radiation dose<br />

Renal trauma<br />

Increasingly used for ureteric calculus detection<br />

Assessment of difficult congenital anomalies and focal masses. Staging of<br />

malignancy<br />

the two kidneys should prompt further investigation<br />

into renal function with a DMSA scan.<br />

Fungal infection<br />

Candidiasis is a fungal infection which is most<br />

commonly seen in infants who are acutely ill or<br />

immunocompromised or in sick ventilated<br />

neonates. Fungal balls dilate and may obstruct the<br />

collecting system of the kidney (Fig. 9.11).<br />

Ultrasound is particularly useful in making the<br />

diagnosis by demonstrating the hyperechoic fungal<br />

balls within the dilated collecting system. Fungal<br />

infection may also undergo haematogenous spread<br />

to the spleen and liver, where it can result in multifocal<br />

abscess formation.<br />

Wilms’ tumour<br />

The most common paediatric renal malignancy,<br />

Wilms’ tumour usually presents before the age of 3<br />

years. Although the lesion generally occurs in previously<br />

fit individuals, there are several known predisposing<br />

conditions, including hemihypertrophy,<br />

Beckwith–Wiedemann syndrome and sporadic<br />

aniridia, with a 30–40% incidence in sporadic aniridia.

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