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THE PAEDIATRIC ABDOMEN 229<br />
Table 9.3<br />
Imaging the paediatric renal tract<br />
Ultrasound<br />
Contrast sonocystography<br />
Diuretic renogram (dynamic) Tc 99m MAG3<br />
Radionuclide cystography (dynamic)<br />
Direct (via catheter or suprapubic injection<br />
of isotope into the bladder) or indirect<br />
(following diuretic renogram)<br />
Cortical scintigraphy (static)—Tc 99m DMSA<br />
Intravenous urography (IVU)<br />
Micturating cystourethrogram<br />
Plain X-ray<br />
CT<br />
MRI<br />
First-line investigation in all cases. Excellent structural detail<br />
Limited sensitivity for duplex kidneys, reflux, ureteral pathology and small<br />
scars<br />
Monitoring of disease progression<br />
Monitoring of treatment<br />
Alternative to X-ray or radionuclide cystography. Poor structural detail,<br />
unsuitable for the demonstration of urethral anomalies<br />
Outlines the pelvicalyceal system. Diagnosis of obstruction and relative renal<br />
function by analysis of excretion curves<br />
Diagnosis of reflux<br />
Demonstrates uptake in the renal cortex<br />
Superior detection of renal scarring in vesicoureteric reflux and acute<br />
pyelonephritis<br />
Demonstration of congenital anomalies, e.g. ectopic or solitary kidney<br />
Analysis of differential renal function<br />
Limited use in children<br />
Assessment of level of ureteric obstruction<br />
Assessment of congenital anomalies, e.g. ectopic ureters and duplex kidney<br />
Postoperative evaluation<br />
Accurate diagnosis of reflux, polyps, diverticula, strictures and urethral<br />
anomalies, but involving a significant radiation dose<br />
Some calculi, mainly those in the ureter<br />
Of limited value in paediatric renal work-up<br />
May show gross spinal anomalies<br />
Reserved mainly for confirmation and staging of malignant tumours, due to<br />
significant radiation dose<br />
Renal trauma<br />
Increasingly used for ureteric calculus detection<br />
Assessment of difficult congenital anomalies and focal masses. Staging of<br />
malignancy<br />
the two kidneys should prompt further investigation<br />
into renal function with a DMSA scan.<br />
Fungal infection<br />
Candidiasis is a fungal infection which is most<br />
commonly seen in infants who are acutely ill or<br />
immunocompromised or in sick ventilated<br />
neonates. Fungal balls dilate and may obstruct the<br />
collecting system of the kidney (Fig. 9.11).<br />
Ultrasound is particularly useful in making the<br />
diagnosis by demonstrating the hyperechoic fungal<br />
balls within the dilated collecting system. Fungal<br />
infection may also undergo haematogenous spread<br />
to the spleen and liver, where it can result in multifocal<br />
abscess formation.<br />
Wilms’ tumour<br />
The most common paediatric renal malignancy,<br />
Wilms’ tumour usually presents before the age of 3<br />
years. Although the lesion generally occurs in previously<br />
fit individuals, there are several known predisposing<br />
conditions, including hemihypertrophy,<br />
Beckwith–Wiedemann syndrome and sporadic<br />
aniridia, with a 30–40% incidence in sporadic aniridia.