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INTERVENTIONAL AND OTHER TECHNIQUES 261<br />

A full scan of the kidney is first performed to<br />

highlight potential problems, for example perirenal<br />

fluid collections, and to establish the safest<br />

and most effective route. The transplanted kidney<br />

lies in an extraperitoneal position and the<br />

chosen route should avoid puncturing the peritoneum,<br />

to minimize the risk of infection. Unlike<br />

the native kidney, the upper pole of the transplanted<br />

kidney is usually chosen to avoid major<br />

blood vessels and the ureter, which pass close to<br />

the lower pole.<br />

The biopsy aims to harvest glomeruli, and the<br />

chosen route should therefore target the renal cortex.<br />

An angle is chosen to include the maximum<br />

thickness of cortex and, where possible, avoid the<br />

renal hilum (Fig. 11.10).<br />

Upper<br />

pole<br />

A<br />

Proposed route<br />

Lower<br />

pole<br />

Complications of ultrasound-guided biopsy<br />

Postprocedure complications such as haematoma<br />

requiring blood transfusion and trauma to adjacent<br />

viscera occur very infrequently when ultrasound<br />

guidance is used. As expected, the risk of complications<br />

is less in fine-needle biopsy than with larger<br />

needles; 4 however, there is no significant difference<br />

in complication rate between a standard 18G Tru-<br />

Cut needle and a 22G Chiba needle. 5 The mortality<br />

and major complication rates vary but using a<br />

standard 18G needle these are approximately<br />

0.018–0.038% and 0.18–0.187% respectively, mortality<br />

being due to haemorrhage in 70%. As a working<br />

figure this means the mortality is approximately<br />

1 in 3300–5400 and morbidity 1 in 530 biopsies<br />

(Table 11.1). 4,6,7 The risk of haemorrhage is<br />

increased in patients with coexistent cirrhosis and is<br />

more likely to occur with malignant than benign<br />

lesions, 8,9 although large haemangiomas also can<br />

carry a significant risk of bleeding.<br />

As with any procedure of this nature, there is a<br />

very small risk of infection, which can be minimized<br />

by using an aseptic technique.<br />

Tumour seeding of the biopsy tract is an uncommon<br />

complication of biopsy and reports of tumour<br />

seeding are associated with repeated passes into the<br />

mass using large needles. Although much talked<br />

about, tumour track seeding is in fact rare, occurring<br />

in approximately 1 in 20 000 biopsies. 7,10 The bestknown<br />

tumours for this are mesothelioma and<br />

hepatoma.<br />

B<br />

Figure 11.10 (A) The transplanted kidney lies in the<br />

iliac fossa and is biopsied with the patient supine. (B)<br />

The needle is seen entering a transplanted kidney<br />

(arrowheads).<br />

Complications following abdominal biopsy are<br />

increased with multiple passes and are at least in<br />

part related to the skill and experience of the<br />

operator.<br />

If the biopsy result is negative or unexpected<br />

then a number of scenarios should be considered<br />

and include sampling error, poor histological specimen,<br />

sonographic or pathological misinterpretation<br />

or indeed a true negative finding. A repeat<br />

biopsy is sometimes justified.<br />

ULTRASOUND-GUIDED DRAINAGE<br />

Many fluid collections are the result of surgical<br />

intervention and often cannot be differentiated<br />

on ultrasound alone. Diagnostic aspiration of

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