Tireoidite linfocítica - Repositório Aberto da Universidade do Porto

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219- MOORE, I., WRIGHT, D.H.: Primary gastric lymphoma - a tumor of mucosa associated lymphoid tissue. A histological and immunohistochemical study of 36 cases. Histopathology 8: 1025-1039, 1984 220-MORI, H., HAMADA, N., DECROOT, L.J.: Studies on thyroglobul in-specific suppressor T cell function in autoimmune thyroid diseases. J Clin Endocrinol Metab 61: 306-312, 1985 221 - MORRIS, H.B., MASON, D.Y., STEIN, H., LENNERT, K.: An immunohistological study of reactive lymphoid tissue. Histopathology 7: 809-823, 1983 222- MUKHTAR, E.D., SMITH, B.R., PYLE, C.A., HALL, R., VICE, P.: Relation of thyroid stimulating immunoglobulins to thyroid function and effects of surgery, radioiodine and antithyroid drugs. Lancet 1: 713-715, 1975 223- NEVE, P.: Ultrastructure of the thyroid in a case of Hashimoto goitre (struma lymphomatosa} Path Europ 1: 234-245, 1966 224-NEVE, P., ERMANS, A.M., BASTENIE, P.A.: Struma lymphomatosa (Hashimoto). In Thyroiditis and Thyroid function. Clinical, morphological and physiopathological studies. Eds: P.A. Bastenie and A.M. Ermans, pp. 109-141. Pergamon Press, Ltd., Oxford, 1972. 225 - NOMA, T., YATA, J. SHISHIBA, Y., INATSUKI, B.: In vitro detection of anti-thyroglobulin antibody forming cells from the lymphocytes of chronic thyroiditis patients and analysis of their regulation. Clin Exp Immunol 49: 565-571, 1982 226 - OGILVIE, R.F.: Endocrine glands - Thyroid. In: Pathological histology. Ed: R.F. Ogilvie, pp. 313-319. E. and S. Livingstone, Edinburgh, 1940 227 - OKAYASU, I., KONG, Y.-C., M., ROSE, N.R.: Effect of castration and sex hormones on experimental autoimmune thyroiditis. Clin Immunol Immunopathol 20: 240-245, 1981 228- OKITA, N., ROW, V.V., VOLPE, R.: Suppressor T-iymphocyte deficiency in Grave's disease and Hashimoto's thyroiditis. J Clin Endocrinol Metab 52: 528-533, 1981 229 - OLIVEIRA, M.C., GUERRA, M.F., CARVALHO, A., SALDANHA, M.C.: O médico perante os nódulos da tireóide. J Médico 113: 229-234, 1982 230- OPPENHEIM, J.J., Gery, I.: Interleukin I is more than an interleukin. Immunol Today 3: 113-119, 1982 231 - ORDONEZ, N.G., IBANEZ, M.L., MACKAY, B., SAMAAN, N.A., HICKEY, R.C.: Functioning oxyphil cell adenomas of parathyroid gland: immunoperoxidase evidence of hormonal activity in oxyphil cells. Amer J Clin Pathol 78: 681-689, 1982 232 - ORGIAZZI, J., WILLIAMS, D.E., CHOPRA, I.J., SOLOMON, D.H.: Human thyroid adenyl cyclase-stimulating activity in immunoglobulin G of patients with Graves' disease. J Clin Endocrinol Metab 42: 341-354, 1976 1 30
233 -OTT, R.A., CALANDRA, D.B., McCALL, A., SHAH, K.H., LAURENCE, A.M., PALOYAN, E.: The incidence of thyroid carcinoma in patients with Hashimoto's thyroiditis and solitary cold nodules. Surgery 98: 1202-1206, 1985 234-PAPENDIECK, L.C., IORCANSKY, S., RIVAROLA, M.A., BERGADA, C: Variations in clinical, hormonal and serological expressions of chronic lymphocytic thyroiditis (CLT) in children and adolescents. Clin Endocrinol 16: 19-28, 1982 235 - PENHALE, W.J., FARMER, A., IRVINE, W.J.: Thyroiditis in T cell-depleted rats. Influence of strain, radiation dose, adjuvants and anti lymphocyte serum. Clin Exp Immunol 21: 362-375, 1975 236-PENHALE, W.J., IRVINE, W.J., INCLIS, J.R., FARMER, A.: Thyroiditis in T-cell depleted rats: supression of the autoallergic response by reconstituition with normal lymphoid cells. Clin Exp Immunol 25: 6-16, 1976 237-PEPERE, A.: Anatomia patológica délie ghiandole a secrezione interna. Tiroide (Ghiandola tiroidea). In: Trattado di anatomia patológica. Ed: P. Foa, PP. 19-60. Unione Tipográfico - Editrice Torinese, Torino, 1922 238 - PEREZ-TAMAYO, R.: Pathology of collagen degradation. A review. Amer J Pathol 92: 509-566, 1978 239-PINCHERA, A., FENZI, CF., BARTALENA, L., CHIOVATO, L., MARCOCCI, C: Thyroiditis. In: The thyroid gland. Ed: M. De Visscher, pp. 413-445. Raven Press, New York, 1980 240 -P1NCHERA, A., FENZI, CF., VITTI, P., CHIOVATO, L., BARTALENA, L., MACCHIA, E., MARIOTTI, S.: Significance of thyroid autoantibodies in autoimmune thyroid disease. In: Autoimmunity and the thyroid. Eds: P.C. Walfish, J.R. Wall and R. Volpé, pp. 139-151. Academic Press, Inc., Orlando, 1985 241 -PINTO, A.D.: Tireoidite experimental auto-imune. Alguns aspectos histológicos e histo-enzimoquími- cos. Dissertação do Acto de Licenciatura, Faculdade de Medicina do Porto, 1966 242-POTT, C: Connective tissue in liver cirrhosis. In: Advances in pathology anatomic and clinical, Vol II. Ed: E. Levy, pp. 111-114, Pergamon Press, Oxford, 1982 243 - PUJOL-BORRELL, R., HANAFUSA, T., CHIOVATO, L., BOTTAZZO, CF.: Lectin-induced expression of DR antigen on human cultured follicular thyroid cells. Nature 304: 71-73, 1983 244-PUJOL-BORREL, R., BOTTAZZO, CF.: The role of HLA-DR in the pathogenesis of autoimmune thyroid disease. In: Autoimmunity and the thyroid. Eds: P.C. Walfish, J.R. Wall and R. Volpé, pp. 37-49. Academic Press, Inc., Orlando, 1985 245- PULVERTAFT, R.J.V., DONIACH, D., ROITT, I.M., HUDSON, R.V.: Citotoxic effects of Hashimoto serum on human thyroid cells in tissue culture. Lancet 2: 214-216, 1959 1 31
Page 1:
- • ■ ,::;^.-v:;V- '.' ■ - :
Page 4 and 5:
Arte 48S, § 35 - A Faculdade não
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descritas por este autor (251). Est
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questões por esclarecer. Estas que
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campo. Foram também excluídos os
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No estudo imunocitoquímico foi uti
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QUADRO I — Principais caracterís
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LA - Resultados Globais RESULTADOS
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QUADRO IV — Distribuição geogr
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QUADRO VI — Principais caracterí
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QUADRO IX — Principais caracterí
Page 24 and 25:
. ' w " If- '■»>~--i. . ■S '
Page 26 and 27:
QUADRO XII — Principais caracter
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de dos casos de tireoidite linfocft
Page 30 and 31:
Fig. H - Hiperplasia difusa A - Pad
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QUADRO XV — Percentagem de célul
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II.B - Tireoglobulina IT.B1 - Tireo
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Fig. 6 - Demonstração imunocitoqu
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microvilosidades longas e numerosas
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Fig. 8 - Tireoidite linfocítica: C
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Fig. 11 - Tireoidite linfocítica:
Page 44 and 45:
Page 46 and 47:
quer sinuosa, com prolongamentos di
Page 48 and 49:
Page 50 and 51:
Fig. 18 Tireoidite linfocítica: In
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fe;#"l8^iï : All: Ï: ; SI ?;
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Fiq 22 - Hiperplasia difusa: Caract
Page 56 and 57: DISCUSSÃO A - LIMITAÇÕES DO "MAT
Page 58 and 59: -interstício. Com efeito, tanto na
Page 60 and 61: em situações muito diversas: neop
Page 62 and 63: 119, 257) e parece ser composta fun
Page 64 and 65: é dirigida para componentes da mat
Page 66 and 67: que ocorra no bócio multinodular (
Page 68 and 69: a nível da célula tireoideia, que
Page 70 and 71: desenvolvei—se na ausência de ti
Page 72 and 73: ASPECTOS CERAIS DA PATOCENESE DA TI
Page 74 and 75: menos de citotoxicidade responsáve
Page 76 and 77: parece compatível com a relativa e
Page 78 and 79: egiões estão em "desequilíbrio"
Page 80 and 81: e a presença de células estimulad
Page 82 and 83: variável de centros germinativos e
Page 84 and 85: que possa ser secundária a process
Page 86 and 87: and IgM (6 ± 596) positive" cells.
Page 88 and 89: I ism, and "aberrant" expression of
Page 90 and 91: trabalhos: Foram utilizados nesta d
Page 92 and 93: 11 -AMINO, N., MIYAI, K., ONISHI, T
Page 94 and 95: 40- BURMAN, P., KARLSSON, F.A., ÕB
Page 96 and 97: 70 -DELESPESSE, G., BASTENIE, P.A.,
Page 98 and 99: 100-FURSZYFER, J., KURLAND, L.T., M
Page 100 and 101: 130 - HEDINCER, Chr.: Geographic pa
Page 102 and 103: 159 KATZ, S.M., VICK ER Y, A.L.: Th
Page 104 and 105: 190-LONDEI, M., LAMB, J.R., BOTTAZZ
Page 108 and 109: 246- RAINES, K.B., BAKER, JR.,U.R.,
Page 110 and 111: 277-SHAMSUDDIN, A.K.M., LANE, R.A.:
Page 112 and 113: 305 - TAYLOR, H.C., SHEELER, L.R.:
Page 114 and 115: 333- WOOLNER, L.B., McCONAHEY, W.M.
Page 116 and 117: Características da interface epit
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